DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ktub and TLP2

DIOPT Version :9

Sequence 1:	NP_611549.2	Gene:	ktub / 37400	FlyBaseID:	FBgn0015721	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_001031369.1	Gene:	TLP2 / 816344	AraportID:	AT2G18280	Length:	394	Species:	Arabidopsis thaliana

Alignment Length:	286	Identity:	97/286 - (33%)
Similarity:	146/286 - (51%)	Gaps:	46/286 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   227 QPAPQGVLYKCRITRDRKGMDRGLFPIYYLHLERDYGKKIFLLGGRKRKKSKTSNYIVSCDPTDL 291
            ||.|:....:|.|.|:|.   ...:.:||..:..:......||..|:.:::..:::|:|....:.
plant   111 QPGPRDSPIQCFIKRNRA---TATYILYYGLMPSETENDKLLLAARRIRRATCTDFIISLSAKNF 172

  Fly   292 SRNADGFCGKLRSNVFGTSFTVFDNGNKEST-------------ESPRL-----DLAVIIYDTNI 338
            ||::..:.|||||...||.||::||....||             .:|:|     .:..|.|:.|:
plant   173 SRSSSTYVGKLRSGFLGTKFTIYDNQTASSTAQAQPNRRLHPKQAAPKLPTNSSTVGNITYELNV 237

  Fly   339 LGFKGPRNM-----------TVILPGMTEDDQRVKISSADPKQQGILDLWKMKN-----MDNIVE 387
            |..:|||.|           .:..|.:.:..:....||..||.:.|....::.:     .|..:.
plant   238 LRTRGPRRMHCAMDSIPLSSVIAEPSVVQGIEEEVSSSPSPKGETITTDKEIPDNSPSLRDQPLV 302

  Fly   388 LHNKTPVWNDETQSYVLNFHGRVTQASVKNFQLVHDSDP---------EYIVMQFGRTSEDVFTM 443
            |.||:|.|:::.|.:.|||.||||.|||||||||.:.|.         |.:::|||:..:|:|||
plant   303 LKNKSPRWHEQLQCWCLNFKGRVTVASVKNFQLVAEIDASLDAPPEEHERVILQFGKIGKDIFTM 367

  Fly   444 DYRYPLCAMQAFAIALSSFDGKIACE 469
            ||||||.|.|||||.:||||.|.|||
plant   368 DYRYPLSAFQAFAICISSFDTKPACE 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ktub	NP_611549.2	Tub	228..462	CDD:279506	89/276 (32%)
TLP2	NP_001031369.1	F-box-like	48..>91	CDD:289689
TLP2	NP_001031369.1	Tub	112..386	CDD:279506	89/276 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	147	1.000	Domainoid score	I1448
eggNOG	1	0.900	-	-		E1_KOG2502
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I1660
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1445357at2759
OrthoFinder	1	1.000	-	-		FOG0000431
OrthoInspector	1	1.000	-	-		otm2426
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR16517
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X288
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.970