Protein Alignment ktub and TULP2

DIOPT Version :9

• Sequence 1: NP_611549.2
• Gene: ktub / 37400
• FlyBaseID: FBgn0015721
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_003314.2
• Gene: TULP2 / 7288
• HGNCID: 12424
• Length: 520
• Species: Homo sapiens
• Alignment Length: 541
• Identity: 183/541 - (33%)
• Similarity: 258/541 - (47%)
• Gaps: 125/541 - (23%)

  Fly     7 RNQKMEQQRQLMEAYIRQKRASPGMVQAS-------------------DLQINRPMSGMRSNSRE 52
            |.||:||||:|.|...||||....||||:                   |..:..|.  :|....|
Human    21 RLQKLEQQRRLFEKKQRQKRQELLMVQANPDASPWLWRSCLREERLLGDRGLGNPF--LRKKVSE 83

  Fly    53 LHAYDGPMQFISSPQNPDQILTNGSPGGINPVAMNTS-RNHSNNMRSLSTINQEGKW-------- 108
            .|.                      |.||:......| .......|.|.|...|..:
Human    84 AHL----------------------PSGIHSALGTVSCGGDGRGERGLPTPRTEAVFRNLGLQSP 126

  Fly   109 --SYTPRKADL-IEEISSHELEDEESSPVTVIEQHQQSASHSANSTQS-QKPRARQHSFSDNLD- 168
              |:.|..:|. :||:|   :|:...||    ...:||........|: |:|..|....||:.|
Human   127 FLSWLPDNSDAELEEVS---VENGSVSP----PPFKQSPRIRRKGWQAHQRPGTRAEGESDSQDM 184

  Fly   169 ----------------------------EDDYTNRNVAGAAPVRPAGMASSPYKDATLDGSSNGT 205
                                        |:|...:..|..:    .|..||...:..|..:..|.
Human   185 GDAHKSPNMGPNPGMDGDCVYENLAFQKEEDLEKKREASES----TGTNSSAAHNEELSKALKGE 245

  Fly   206 GNGTGGES----------------EGDVIGNIDQFVMQPAPQGVLYKCRITRDRKGMDRGLFPIY 254
            | ||..:.                |.|    ::.:|::||..|.:.:|.:|||:.|:|:||||:|
Human   246 G-GTDSDHMRHEASLAIRSPCPGLEED----MEAYVLRPALPGTMMQCYLTRDKHGVDKGLFPLY 305

  Fly   255 YLHLERDYGKKIFLLGGRKRKKSKTSNYIVSCDPTDLSRNADGFCGKLRSNVFGTSFTVFDNG-- 317
            ||:||.....:.|||.||||::||||||::|.|||.|||:.|.|.||:|||||.|.||:||||
Human   306 YLYLETSDSLQRFLLAGRKRRRSKTSNYLISLDPTHLSRDGDNFVGKVRSNVFSTKFTIFDNGVN 370

  Fly   318 -NKE----STESPRLDLAVIIYDTNILGFKGPRNMTVILPGMTEDDQRVKISSADPKQQGILDLW 377
             ::|    :|...|.:|..:.|:.|:||:.|||.|||||||....:||:.:...: :|:.:|..:
Human   371 PDREHLTRNTARIRQELGAVCYEPNVLGYLGPRKMTVILPGTNSQNQRINVQPLN-EQESLLSRY 434

  Fly   378 KMKNMDNIVELHNKTPVWNDETQSYVLNFHGRVTQASVKNFQLVHDSDPEYIVMQFGRTSEDVFT 442
            :..:...::.||||||.|:.|...|.||||||||:|||||||:|.....|::|:||||...|.||
Human   435 QRGDKQGLLLLHNKTPSWDKENGVYTLNFHGRVTRASVKNFQIVDPKHQEHLVLQFGRVGPDTFT 499

  Fly   443 MDYRYPLCAMQAFAIALSSFD 463
            ||:.:|...:|||:|.||||:
Human   500 MDFCFPFSPLQAFSICLSSFN 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ktub	NP_611549.2	Tub	228..462	CDD:279506	119/240 (50%)
TULP2	NP_003314.2	Tub_N	27..241	CDD:318529	51/248 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	141..236		20/105 (19%)
		Tub	279..519	CDD:307359	119/240 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143586
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2502
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1445357at2759
OrthoFinder	1	1.000	-	-		FOG0000431
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR16517
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X288
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.810