Protein Alignment ktub and TULP1

DIOPT Version :9

• Sequence 1: NP_611549.2
• Gene: ktub / 37400
• FlyBaseID: FBgn0015721
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_003313.3
• Gene: TULP1 / 7287
• HGNCID: 12423
• Length: 542
• Species: Homo sapiens
• Alignment Length: 521
• Identity: 200/521 - (38%)
• Similarity: 272/521 - (52%)
• Gaps: 104/521 - (19%)

  Fly    41 RPMSGMRSNSRELHAYDGPMQFISSPQNPDQILT-----NGSPGGINPVAMNTSRNHSNNMRSLS 100
            ||....|...:...|.:.|....|.|:.|....|     ..||......|..|.  ::..:|...
Human    34 RPAPAQRLRKKRTEAPESPCPTGSKPRKPGAGRTGRPREEPSPDPAQARAPQTV--YARFLRDPE 96

  Fly   101 TINQEGKWSYTPRKADLIEEISSHELEDEESSPVTVIEQHQQ-------------SASHSANSTQ 152
            ...::.:.::...:|...|:....|.||||.......|:.::             ||.......:
Human    97 AKKRDPRETFLVARAPDAEDEEEEEEEDEEDEEEEAEEKKEKILLPPKKPLREKSSADLKERRAK 161

  Fly   153 SQKPRARQHSFSDNLDEDD----------------------YTNRNVAGAAPVRPAGMASSPYKD 195
            :|.||.       :|...|                      .|.:..:|.|...|:|..:|..|.
Human   162 AQGPRG-------DLGSPDPPPKPLRVRNKEAPAGEGTKMRKTKKKGSGEADKDPSGSPASARKS 219

  Fly   196 ATL-----DGS-------SNGTGNGTGGESEGD-----VIGNIDQ-------------------- 223
            ...     :||       ..||..|...|.|.:     ||...:|
Human   220 PAAMFLVGEGSPDKKALKKKGTPKGARKEEEEEEEAATVIKKSNQKGKAKGKGKKKAKEERAPSP 284

  Fly   224 ---------FVMQPAPQGVLYKCRITRDRKGMDRGLFPIYYLHLERDYGKKIFLLGGRKRKKSKT 279
                     ||::|||||...:||:|||:||||||::|.|:|||:.:  ||:|||.|||||:|||
Human   285 PVEVDEPREFVLRPAPQGRTVRCRLTRDKKGMDRGMYPSYFLHLDTE--KKVFLLAGRKRKRSKT 347

  Fly   280 SNYIVSCDPTDLSRNADGFCGKLRSNVFGTSFTVFDNGN------KESTESPRLDLAVIIYDTNI 338
            :||::|.|||:|||..:.|.||||||:.|..|||||||.      ..:..|.|.:||.:||:||:
Human   348 ANYLISIDPTNLSRGGENFIGKLRSNLLGNRFTVFDNGQNPQRGYSTNVASLRQELAAVIYETNV 412

  Fly   339 LGFKGPRNMTVILPGMTEDDQRVKISSADPKQQGILDLWKMKNMDNIVELHNKTPVWNDETQSYV 403
            |||:|||.||||:|||:.:::||.|...: ...|:|..|:.|.:::::|||||.|||||::.||.
Human   413 LGFRGPRRMTVIIPGMSAENERVPIRPRN-ASDGLLVRWQNKTLESLIELHNKPPVWNDDSGSYT 476

  Fly   404 LNFHGRVTQASVKNFQLVHDSDPEYIVMQFGRTSEDVFTMDYRYPLCAMQAFAIALSSFDGKIAC 468
            |||.||||||||||||:||..||:|||:||||.:||.||:||||||||:|||||||||||||:||
Human   477 LNFQGRVTQASVKNFQIVHADDPDYIVLQFGRVAEDAFTLDYRYPLCALQAFAIALSSFDGKLAC 541

  Fly   469 E 469
            |
Human   542 E 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ktub	NP_611549.2	Tub	228..462	CDD:279506	144/239 (60%)
TULP1	NP_003313.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..289		46/263 (17%)
		PHA03282	<3..82	CDD:165539	11/47 (23%)
		Tub	298..535	CDD:279506	144/239 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	336	1.000	Domainoid score	I1121
eggNOG	1	0.900	-	-		E1_KOG2502
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	369	1.000	Inparanoid score	I2142
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1445357at2759
OrthoFinder	1	1.000	-	-		FOG0000431
OrthoInspector	1	1.000	-	-		otm41820
orthoMCL	1	0.900	-	-		OOG6_101683
Panther	1	1.100	-	-	O	PTHR16517
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X288
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.830