Protein Alignment ktub and tub-1

DIOPT Version :9

• Sequence 1: NP_611549.2
• Gene: ktub / 37400
• FlyBaseID: FBgn0015721
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_495710.1
• Gene: tub-1 / 174312
• WormBaseID: WBGene00006655
• Length: 426
• Species: Caenorhabditis elegans
• Alignment Length: 499
• Identity: 194/499 - (38%)
• Similarity: 273/499 - (54%)
• Gaps: 103/499 - (20%)

  Fly     1 MSGINSR--NQKMEQQRQLMEAYIRQKR-ASPGMVQASDLQINRPMSGMRSNS-RELHAYDGPMQ 61
            |:..||:  ...:::||:::|...:||| .|.|.|:.:.       :.|..|| ::...:|..:.
 Worm     1 MTDTNSQWIEMNLQRQRKMLEDKQKQKRHQSAGSVRTTS-------TAMSMNSMKDYPTFDNSLP 58

  Fly    62 FISSPQNPDQILTNGSPGGINPVAMNTSRNHSNNMRSLSTINQEGKWSYTPRKADLIEEISSHEL 126
            |        .|..|.|..    |:|||..     :.:...|.|       ||.
 Worm    59 F--------SISDNSSVS----VSMNTPL-----IPTQDPIAQ-------PRM------------ 87

  Fly   127 EDEESSPVTVIEQHQQS----ASHSANSTQSQKPRARQHS--FSDNLDEDDYTNRNVAGAAPVRP 185
               :|.|....:|.|:|    ..:..|...::..:....|  .||:.|||              .
 Worm    88 ---QSMPRQQPQQVQESLISIGDYPDNDINAKLSKVNLTSCVVSDDEDED--------------K 135

  Fly   186 AGMASSPYK-DATLDGSSNGTGNGTGGESEGDVI-------GNIDQFVMQPAPQGVLYKCRITRD 242
            ...|.||:. |...|            ....:|:       .|:.:||..||.:..||||.|||.
 Worm   136 RSYADSPWNTDVVAD------------RIPSEVLPDYNFIKNNLAKFVEDPAVEHCLYKCSITRQ 188

  Fly   243 RKGMDRGLFPIYYLHLER---DYGKKIFLLGGRKRKKSKTSNYIVSCDPTDLSRNADGFCGKLRS 304
            :.|:|:|:||.|:||||.   |..:|||||..||||||.|:||::|.|||:|||..:|:|.|:||
 Worm   189 KSGVDKGMFPTYFLHLEEFDTDKRQKIFLLAARKRKKSTTANYLLSTDPTNLSREGEGYCAKVRS 253

  Fly   305 NVFGTSFTVFDNGN--KESTE--SPRLDLAVIIYDTNILGFKGPRNMTVILPGM---TEDDQRVK 362
            |..||.|||:|:|.  |::|.  :.|.:||.:||:||:|||||||.||:::||:   ||:...|:
 Worm   254 NALGTQFTVYDSGQNPKKTTNHAAIRQELAAVIYETNVLGFKGPRKMTIVMPGIEPPTENRPAVR 318

  Fly   363 ISSADPKQ--QGILDLWKMKNMDNIVELHNKTPVWNDETQSYVLNFHGRVTQASVKNFQLVHDSD 425
             ....|.|  ..:|:.:::.::|::..|.||:|.|||||||||||||||||||||||||::|.|.
 Worm   319 -CPVRPIQDKHTLLERYRLNDLDSLKILSNKSPQWNDETQSYVLNFHGRVTQASVKNFQIIHQSS 382

  Fly   426 PEYIVMQFGRTSEDVFTMDYRYPLCAMQAFAIALSSFDGKIACE 469
            ||||||||||.|:|.||||:||||.|:|||.||::||.||:|||
 Worm   383 PEYIVMQFGRISDDEFTMDFRYPLSAVQAFGIAMTSFHGKLACE 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ktub	NP_611549.2	Tub	228..462	CDD:279506	138/245 (56%)
tub-1	NP_495710.1	Tub	174..419	CDD:279506	138/245 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	279	1.000	Domainoid score	I898
eggNOG	1	0.900	-	-		E1_KOG2502
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	297	1.000	Inparanoid score	I1655
Isobase	1	0.950	-	0	Normalized mean entropy	S3334
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1445357at2759
OrthoFinder	1	1.000	-	-		FOG0000431
OrthoInspector	1	1.000	-	-		oto18533
orthoMCL	1	0.900	-	-		OOG6_101683
Panther	1	1.100	-	-	LDO	PTHR16517
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2866
SonicParanoid	1	1.000	-	-		X288
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.810