Protein Alignment CG9394 and PHO81

DIOPT Version :10

• Sequence 1: NP_611548.1
• Gene: CG9394 / 37399
• FlyBaseID: FBgn0034588
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: NP_011749.3
• Gene: PHO81 / 853148
• SGDID: S000003465
• Length: 1178
• Species: Saccharomyces cerevisiae
• Alignment Length: 662
• Identity: 124/662 - (18%)
• Similarity: 237/662 - (35%)
• Gaps: 203/662 - (30%)

  Fly    79 PVLGAWQAGRAVLLNRTAILNVWSASVEIPQNSSVEYRYFAAAVGQSGAVQIRRWESHVQA---- 139
            |:..|.::|.:.::  |.:|. .:|.::|..::.....::|.            |||||..
Yeast   595 PIFYAVRSGHSEVI--TELLK-HNARLDIEDDNGHSPLFYAL------------WESHVDVLNAL 644

  Fly   140 --RTFN---------TTKFSGNRSDEFGLIGNERQLSRGWLQDS-----------------GNIL 176
              |..|         .::.|..|.:...|..|:.:.... :|||                 .|.|
Yeast   645 LQRPLNLPSAPLNEINSQSSTQRLNTIDLTPNDDKFDLD-IQDSIPDFALPPPIIPLRKYGHNFL 708

  Fly   177 QLKLFREALSLEEQPEVGQEKLRLRLQPVDPKTLAPILSSARANVEYVRMAYGDSKLRVQPEYGV 241
            :.|:|   :.|:.:|  |.|.::|      .:....|:||:..     |:....:...:.|...:
Yeast   709 EKKIF---IKLKLRP--GLESIKL------TQDNGIIMSSSPG-----RITLSSNLPEIIPRNVI 757

  Fly   242 -PYATGDILMFHVNLEQLDRVAYLVEVYAEQPDEDLV---------------------RLLGYSH 284
             |..:|:|..|..::.:.:......|:..:..|.:::                     |::..:.
Yeast   758 LPVRSGEINNFCKDISETNDEEDDDEISEDHDDGEIIFQVDSIDDFSMDFEIFPSFGTRIIAKTT 822

  Fly   285 LLHTSFSGTEGDVSIDLIS----PLWQ---RVVGQLRIEYLHIRPMEKDGFDLRTSFANYWRSNW 342
            .:...|.    .|:|:.|:    ||:.   ..:|.|.::|..|.|...:...: .::..||:|.
Yeast   823 AMPFLFK----KVAINSIATMNLPLFDTRLNNIGSLTLDYQIIFPYPGNPLKI-INYEPYWKST- 881

  Fly   343 TALEIGHRGLGKSLTVTTNAAPLIENTVATMLASSELGADLVEFDVQLTSDLVPIIHHDFSIRVC 407
                      |..|..::..        ...:.||.|....:                  |:.||
Yeast   882 ----------GSDLMTSSKD--------GNFVTSSSLNGSFI------------------SVLVC 910

  Fly   408 -------IDSKTPTSKDDLTEVLLKDISYEQLKDLKTYQIVGNKIVEYP------AHNNVEPPE- 458
                   :.:..|..:...|::||.|::.|||:          |:|:|.      :.:.|...:
Yeast   911 ALNDETIVAAPKPYVEFKGTKILLNDLTKEQLE----------KVVDYDFGKIDGSFDEVTLKQY 965

  Fly   459 --QRLFPTLQDFFERVNLSTGFDIEIKWP-QQRADGL-FESEQTLDKNLFADRILAVVRRH---- 515
              .|:.| |:...|.:..|....|.:.:| .:..|.: .:....::.|.|.|::|.::..|
Yeast   966 LSSRVVP-LRSLLEVIPGSAQLVIRVYFPTDKEIDTIPIKISPFININQFIDKLLLIIFEHERFL 1029

  Fly   516 ---GCGRLN--VIKSFDADLCSLLRFKQHMYPVL--------------FLSSS----KENVFNDP 557
               |.|.:.  |..|.:.:.||:|.:||..:|||              |:..:    ||...|..
Yeast  1030 RHSGSGSMRQIVFSSCNWEACSILNWKQPNFPVLLQMKNLLRDSTTGKFVGDTPNCLKELAVNPQ 1094

  Fly   558 RTS-------TVEQSVNFAQAFDLGGVSPNAVFVKADPGLVQRAKAQVPIVLLWGSDLKDRESID 615
            :.|       .:...|.||...:|.||:.....:|..|.|.:..| |..::|:......|:...|
Yeast  1095 KMSYLNTELINIHTMVQFAMNNNLLGVTLPYEVLKICPSLARIIK-QNGLLLIASVGENDQIPAD 1158

  Fly   616 WFLQQGPTGVIY 627
                .|.:|:.|
Yeast  1159 ----GGYSGIYY 1166

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9394	NP_611548.1	CBM20	47..169	CDD:449530	19/104 (18%)
		GDPD_GDE5	345..630	CDD:176549	67/335 (20%)
PHO81	NP_011749.3	SPX_PHO81_NUC-2_like	2..159	CDD:269904
		ANKYR	395..690	CDD:440430	22/110 (20%)
		ANK repeat	423..456	CDD:293786
		ANK repeat	458..495	CDD:293786
		ANK repeat	508..540	CDD:293786
		ANK repeat	561..588	CDD:293786
		ANK repeat	590..622	CDD:293786	7/29 (24%)
		GDPD_NUC-2_fungi	875..1172	CDD:176520	70/345 (20%)