DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34396 and TOK1

DIOPT Version :9

Sequence 1:	NP_611547.2	Gene:	CG34396 / 37398	FlyBaseID:	FBgn0085425	Length:	975	Species:	Drosophila melanogaster
Sequence 2:	NP_012442.1	Gene:	TOK1 / 853352	SGDID:	S000003629	Length:	691	Species:	Saccharomyces cerevisiae

Alignment Length:	391	Identity:	75/391 - (19%)
Similarity:	132/391 - (33%)	Gaps:	123/391 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   604 GLRRYPGQKSWNFVNCFIFCWTVITTIGYGHITPKTGMGRSLTIVYAIIGIPMFLIVLADLGKLF 668
            |...:.|.....:.|...||...:.|:|.|.|.||:...:.:.:::::.|:.:..::
Yeast   262 GAGMFSGLLHITYGNALYFCTVSLLTVGLGDILPKSVGAKIMVLIFSLSGVVLMGLI-------- 318

  Fly   669 TRCVKFLWVYVRRMYYTRSCRRIRKQQQIRSAMTGFNTMYDMAIRRPSMFFSNSAPENDEESQAD 733
                         ::.|||.  |:|..                  .|..||..
Yeast   319 -------------VFMTRSI--IQKSS------------------GPIFFFHR------------ 338

  Fly   734 AEAARSVGTSH--PETPTSPYPETFEV-----------DDEFNLPVSVASLLLITYILLGSFGFL 785
            .|..||....|  ..:......|.|::           ...|:|.|::|  :.:.:.|||:..|.
Yeast   339 VEKGRSKSWKHYMDSSKNLSEREAFDLMKCIRQTASRKQHWFSLSVTIA--IFMAFWLLGALVFK 401

  Fly   786 MMEPSWTPLDAFYYVFISMSTIGFGDLVP----SNPFYVMVSMIYLMFGLALTSMFINVVQIKLS 846
            ..| :|:..:..|:.|:.:.|||:||..|    ...|:|    |:.:..:.|....::.|...|.
Yeast   402 FAE-NWSYFNCIYFCFLCLLTIGYGDYAPRTGAGRAFFV----IWALGAVPLMGAILSTVGDLLF 461

  Fly   847 DHFKMASAKVGATIG-----------------MNMTSELGDE-----GGSQVKTPSELASVHGSR 889
            |.......|:|.:..                 |..|.|:.:|     |..:..|.|.    ..|:
Yeast   462 DISTSLDIKIGESFNNKVKSIVFNGRQRALSFMVNTGEIFEESDTADGDLEENTTSS----QSSQ 522

  Fly   890 LDRIEEDGQEANGNGHSPVPPLTSILRAPRPLSPASNGVDANGVGADAVGAGDVTPPPLLPRRQV 954
            :....::..|.|.:|.:..|  .|:..:...||.||                  :|..:||...|
Yeast   523 ISEFNDNNSEENDSGVTSPP--ASLQESFSSLSKAS------------------SPEGILPLEYV 567

  Fly   955 S 955
            |
Yeast   568 S 568

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34396	NP_611547.2	RILP-like	135..>217	CDD:304877
		Ion_trans_2	<614..670	CDD:285168	10/55 (18%)
		Ion_trans_2	771..847	CDD:285168	20/79 (25%)
TOK1	NP_012442.1	Ion_trans_2	253..328	CDD:400301	16/88 (18%)
TOK1	NP_012442.1	Ion_trans_2	388..462	CDD:400301	20/78 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345207
Domainoid	1	1.000	56	1.000	Domainoid score	I2685
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.930