DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34396 and kcnk5a

DIOPT Version :9

Sequence 1:	NP_611547.2	Gene:	CG34396 / 37398	FlyBaseID:	FBgn0085425	Length:	975	Species:	Drosophila melanogaster
Sequence 2:	NP_001032478.1	Gene:	kcnk5a / 570159	ZFINID:	ZDB-GENE-051113-112	Length:	513	Species:	Danio rerio

Alignment Length:	327	Identity:	83/327 - (25%)
Similarity:	128/327 - (39%)	Gaps:	107/327 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   530 LICMAML--LGFGGLLFRYTEGAAENIYKCEVRKVKRDFIDRLWDVSHNMREEDWKSLARQKLRS 592
            |:..|::  |..|..:|:..|   |..::..|||.:.|....|         :.:..|.:..|..
Zfish     7 LLTSAIIFYLSIGAAIFQVIE---EPNWEIAVRKYRADKESIL---------KQYPCLTKADLDY 59

  Fly   593 FEDELNNLAELGLRRYPGQK---SWNFVNCFIFCWTVITTIGYGHITPKTGMGRSLTIVYAIIGI 654
            ..:.:::.|..|: ...|.|   :||:.|..||..|||||||||:|.|||..||...|.|.:.|:
Zfish    60 ILEVVSDAAGQGI-TITGDKTFNNWNWPNAVIFAATVITTIGYGNIAPKTPSGRVFCIFYGLFGV 123

  Fly   655 PMFLIVLADLGKLFTRCVKFL-WVYVRRMYYTRSCRRIRKQQQIRSAMTGFNTMYDMAIRRPSMF 718
            |:....:::|||.|....|.| |      |.|:....:||.|
Zfish   124 PLCFTWISELGKFFGGRAKHLGW------YLTKKGVTLRKTQ----------------------- 159

  Fly   719 FSNSAPENDEESQADAEAARSVGTSHPETPTSPYPETFEVDDEFNLPVSVASLL--LITYILLGS 781
                                                         |..:...||  ::.::::..
Zfish   160 ---------------------------------------------LTCTAVFLLWGVLIHLVIPP 179

  Fly   782 FGFLMMEPSWTPLDAFYYVFISMSTIGFGDLV---------PSNPFYVMVSMIYLMFGLALTSMF 837
            |.|:..| .||.::..|:.|::::||||||||         |:...|.:...|||  |||..|:|
Zfish   180 FVFMTQE-GWTYIEGLYFSFVTLTTIGFGDLVAGVDPNAEYPTLYRYFVEVWIYL--GLAWLSLF 241

  Fly   838 IN 839
            .|
Zfish   242 FN 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34396	NP_611547.2	RILP-like	135..>217	CDD:304877
		Ion_trans_2	<614..670	CDD:285168	28/55 (51%)
		Ion_trans_2	771..847	CDD:285168	28/80 (35%)
kcnk5a	NP_001032478.1	Ion_trans_2	<81..137	CDD:285168	27/55 (49%)
kcnk5a	NP_001032478.1	Ion_trans_2	171..243	CDD:285168	25/74 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810