DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34396 and kcnk1b

DIOPT Version :9

Sequence 1:	NP_611547.2	Gene:	CG34396 / 37398	FlyBaseID:	FBgn0085425	Length:	975	Species:	Drosophila melanogaster
Sequence 2:	NP_001277277.1	Gene:	kcnk1b / 561206	ZFINID:	ZDB-GENE-090312-78	Length:	337	Species:	Danio rerio

Alignment Length:	337	Identity:	80/337 - (23%)
Similarity:	130/337 - (38%)	Gaps:	112/337 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   527 IAYLICMAMLLGFGGLLFRYTEGAAENIYKCEVRKVKRDFIDRLWDVSHNMREEDWKSLARQKLR 591
            :.|||       ||.::|...|...|:..:.::|::||.|:            ::.:.|:.::|.
Zfish    31 VLYLI-------FGAVVFSSVELPYEDDLRQQLREIKRLFL------------QEHQCLSEERLE 76

  Fly   592 SFED---ELNNLAELGLRRYPGQKSWNFVNCFIFCWTVITTIGYGHITPKTGMGRSLTIVYAIIG 653
            .|..   |.:|.....|.......:|:|.:...|..||::|.||||..|.:..|::..|:|::||
Zfish    77 RFLSKALEASNYGVSILNNASASWNWDFTSSLFFASTVLSTTGYGHTAPLSDGGKAFCIIYSVIG 141

  Fly   654 IPMFLIVLADLGKLFTRCVKFLWVYVRRMYYTRSCRRIRKQQQIRSAMTGFNTMYDMAIRRPSMF 718
            ||..|:.|       |..|:.:.||                                :..||.|:
Zfish   142 IPFTLLFL-------TAVVQRIMVY--------------------------------STWRPIMY 167

  Fly   719 FSNSAPENDEESQADAEAARSVGTSHPETPTSPYPETFEVDDEFNLPVSV-ASLLLIT----YIL 778
            ...                 ..|.|.|                  |...| |:||.:.    :.|
Zfish   168 VHT-----------------RWGLSKP------------------LVALVHATLLAVVAVSCFFL 197

  Fly   779 LGSFGFLMMEPSWTPLDAFYYVFISMSTIGFGDLVPSNPF-------YVMVSMIYLMFG----LA 832
            :.:..|..:|.:|..|::||:.|||:||||.||.||...|       |.:...:||:.|    |.
Zfish   198 IPAAIFSALEENWNFLESFYFCFISLSTIGLGDYVPGEAFNQRFRELYKLGITVYLLLGLIAMLV 262

  Fly   833 LTSMFINVVQIK 844
            :...|..:.|:|
Zfish   263 VLETFCELQQLK 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34396	NP_611547.2	RILP-like	135..>217	CDD:304877
		Ion_trans_2	<614..670	CDD:285168	20/55 (36%)
		Ion_trans_2	771..847	CDD:285168	29/89 (33%)
kcnk1b	NP_001277277.1	Ion_trans_2	<99..157	CDD:285168	22/64 (34%)
kcnk1b	NP_001277277.1	Ion_trans_2	192..267	CDD:285168	24/74 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810