DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34396 and sand

DIOPT Version :9

Sequence 1:	NP_611547.2	Gene:	CG34396 / 37398	FlyBaseID:	FBgn0085425	Length:	975	Species:	Drosophila melanogaster
Sequence 2:	NP_610349.1	Gene:	sand / 35777	FlyBaseID:	FBgn0033257	Length:	395	Species:	Drosophila melanogaster

Alignment Length:	366	Identity:	108/366 - (29%)
Similarity:	175/366 - (47%)	Gaps:	78/366 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   504 EWKRLKLDYPQKVKELRQLRNRCIAYLICMAMLLGFGGLLFRYTEGAAENIYKCEVRKVKRDFID 568
            |::|||.:.|.:. ..|.....|::                |..|..||||...:....:|...|
  Fly    58 EYERLKSEKPHRF-IARNFSGECLS----------------RIWELTAENISFFDHHAYRRRVND 105

  Fly   569 RLWDVSHNMREEDWKSLARQKLRSFEDELNNLAELGLRRYPGQKSWNFVNCFIFCWTVITTIGYG 633
            .|.|..        :::.:::|:.                |..:.|:|...|::..|||||||||
  Fly   106 VLLDYQ--------RAIVKKQLKG----------------PDVEQWSFSGAFLYSLTVITTIGYG 146

  Fly   634 HITPKTGMGRSLTIVYAIIGIPMFLIVLADLGKLFTRCVKFLWVYVRRMYYTRSC-----RRI-- 691
            :|||.:..|:.:||:|||||:|:||:.|:::|.:..:  .|.|:| .::...|.|     |||
  Fly   147 NITPHSECGKLVTILYAIIGMPLFLLYLSNIGDVLAK--SFKWIY-SKVCLCRICPGVAKRRIIR 208

  Fly   692 --RKQQQIRSAMTGFNTMYDMAIRRPSMFF--------SNSAPENDEESQADAEAARSVGTSHPE 746
              ||.:|:..|:    .|:||...|.|..:        |||:  :.|.:::..:::..|...:.|
  Fly   209 ERRKMRQLARAL----QMHDMENARGSSSYTSTSSTTSSNSS--SSEYTRSSRQSSSLVDIQYTE 267

  Fly   747 TPTSPYPETFEVDDEFNLPVSVASLLLITYILLGSFGFLMMEPSWTPLDAFYYVFISMSTIGFGD 811
            :.:....|.....||..:||:|...:::.|||.|:..|...| .|..||..|:..||:|:|||||
  Fly   268 SDSDIEREIRGSTDEITVPVTVCVFVMVGYILWGALLFGRWE-DWNYLDGSYFCLISLSSIGFGD 331

  Fly   812 LVPSNPFY------VMVSM----IYLMFGLALTSMFINVVQ 842
            |||.:...      |.||.    |||:.|:|:.:|..|::|
  Fly   332 LVPGDRVITADRDKVEVSFILCAIYLLLGMAVIAMCFNLMQ 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34396	NP_611547.2	RILP-like	135..>217	CDD:304877
		Ion_trans_2	<614..670	CDD:285168	28/55 (51%)
		Ion_trans_2	771..847	CDD:285168	32/82 (39%)
sand	NP_610349.1	Ion_trans_2	123..183	CDD:285168	28/59 (47%)
sand	NP_610349.1	Ion_trans_2	292..377	CDD:285168	32/82 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461321
Domainoid	1	1.000	56	1.000	Domainoid score	I2685
eggNOG	1	0.900	-	-		E1_KOG1418
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5602
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D542195at33208
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	1	1.000	-	-		otm24931
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.800