DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG34396 and twk-12

DIOPT Version :9

Sequence 1:NP_611547.2 Gene:CG34396 / 37398 FlyBaseID:FBgn0085425 Length:975 Species:Drosophila melanogaster
Sequence 2:NP_505731.3 Gene:twk-12 / 192074 WormBaseID:WBGene00006667 Length:684 Species:Caenorhabditis elegans


Alignment Length:484 Identity:107/484 - (22%)
Similarity:176/484 - (36%) Gaps:134/484 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   522 LRNRCIAYLICMAMLLGFGGLLFRYTEGAAE----NIYKCEVRKVKRDFIDRLWDVSHN--MREE 580
            :|.|.....:.:.....||..|||..|..|:    :::......|:|...:| |...|.  :...
 Worm    14 IRLRSYYKFLLLIAYTAFGAWLFRTYELQADIKRRSVFGNTTNLVRRQLAER-WIEMHKDAVLRN 77

  Fly   581 DWKSLARQKLRSFE---DELNNLAELGLRRYPGQKSWNFVNCFIFCWTVITTIGYGHITPKTGMG 642
            |.....|:...:.|   ||| ||:: .:|....:..|.:.....:...:.||||||:.|.||..|
 Worm    78 DSALRFRRAAEAVEWLLDEL-NLSD-HIRDLSEETPWTWTGAMFYAGQLYTTIGYGYPTTKTDEG 140

  Fly   643 RSLTIVYAIIGIPMFLIVLADLGKLFTRCVKFLWVYVRRMYYTRSCR----RIRKQQQIRSAMTG 703
            |..||.||:.|||.||:.|..:||..::.:|        .||.:..|    ||....::.:...|
 Worm   141 RICTIFYALFGIPCFLMYLKSIGKTLSKKMK--------KYYKKLRRSRVGRILLPTRVTAMKDG 197

  Fly   704 FNTMYDMAIRRPSMFFSNSAPENDEESQADAEAARSVGTSHPETPTSPYPETFEVDDEFNLPVSV 768
            |.                           |.|||.       |....|:            |:.:
 Worm   198 FE---------------------------DPEAAE-------ERKKKPF------------PIPI 216

  Fly   769 ASLLLITYILLGSFGFLMMEPSWTPLDAFYYVFISMSTIGFGDLVPSNPFYVMVSMIYLMFGLAL 833
            |.::||.:|...:..|.:.|.:|....|.|:..:|:||:|.||::...|..::.:.:.::.||||
 Worm   217 AIIMLIIWICFSASMFCIWEDTWVFSSAVYFFIVSISTVGLGDMLFRTPDMMVFNFLLILVGLAL 281

  Fly   834 TSMFINVV--------QIKLSDHFKMAS------------AKVGATIGMNMTSELGDEGGSQVKT 878
            .||...::        |.:..:|.|...            .:....:|:.|...|          
 Worm   282 LSMCFELITDRVAKWKQKRFDEHIKKVQKMAFQVFEKDPFIEEAPPLGIRMAPNL---------- 336

  Fly   879 PSELASVH-----------------GSRLDRI----------EEDGQEANGNGHSP-VPPLTSIL 915
             .::|:.|                 |...|.:          |.|.:||.....|| :..:|:  
 Worm   337 -MQIAATHVSEEKRGFFAEFKDWFAGKVTDNVIQSKLEDSDDESDSEEALEEFDSPQIATVTA-- 398

  Fly   916 RAPRPLSPASNGVDANGVGADAVGAGDVT 944
               ..|...|||.....|...:....|::
 Worm   399 ---NDLIVCSNGAATRRVSKQSYALSDIS 424

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG34396NP_611547.2 RILP-like 135..>217 CDD:304877
Ion_trans_2 <614..670 CDD:285168 24/55 (44%)
Ion_trans_2 771..847 CDD:285168 22/83 (27%)
twk-12NP_505731.3 Ion_trans_2 92..167 CDD:285168 30/76 (39%)
Ion_trans_2 226..>272 CDD:285168 12/45 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1418
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000030
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
43.770

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