DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34396 and twk-29

DIOPT Version :9

Sequence 1:	NP_611547.2	Gene:	CG34396 / 37398	FlyBaseID:	FBgn0085425	Length:	975	Species:	Drosophila melanogaster
Sequence 2:	NP_001021467.1	Gene:	twk-29 / 185828	WormBaseID:	WBGene00006681	Length:	476	Species:	Caenorhabditis elegans

Alignment Length:	425	Identity:	88/425 - (20%)
Similarity:	158/425 - (37%)	Gaps:	119/425 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   518 ELRQLRNRCIA----YLICMAMLLGFGGLLFRYTEGAAENIYKCEVRKVKRDFIDRLWDVSHNMR 578
            |..|...|.||    .::.:.:....||.:|...|...:...|......||..|:.|.:..:.:|
Worm    40 ECLQHNRRAIAVNGFIIVFLIIYTTIGGFIFLNFEFEYQQYMKQNATLEKRLCIESLLNRDNRLR 104

  Fly   579 EEDWKSLARQKLRSFEDELNNLAELGLRR--YPGQKSWNFVNCFIFCWTVITTIGYGHITPKTGM 641
                       |....|....:||..|..  ...:..|:|.:..::...::||:|||.|.|:|..
Worm   105 -----------LTRASDVAAAIAERCLTENVKDDRMQWSFKSAALYSLGILTTLGYGKIEPQTIN 158

  Fly   642 GRSLTIVYAIIGIPMFLIVLADLGKLFTRCVKFLWVYVRRMYYTRSCRRIRKQQQIRSAMTGFNT 706
            ||..|::|...|||:.:|:|.:.|       ::|.....|.....||||.|:
Worm   159 GRISTVIYGFFGIPLTVILLTNFG-------RYLEAMATRFRRLISCRRRRE------------- 203

  Fly   707 MYDMAIRRPSMFFSNSAPENDEESQADAEAARSVGTSHPETPTSPYPETFEVDDEFNLPVSVASL 771
                                                                |::.|:..|....
Worm   204 ----------------------------------------------------DEDENVSGSTLFF 216

  Fly   772 LLITYILLGSFGFLMMEPSWTPLDAFYYVFISMSTIGFGDLVPSNPFYVMVSMIYLMFGLALTSM 836
            :::.|::||:....:|...:...:..||.||.::.|.:||::|.|.:::.:|:.|:..|||::::
Worm   217 IVLVYLILGATMIPLMSGQFDFFNGIYYAFICLTAIEYGDIIPQNNWFLPISVFYMCTGLAISTI 281

  Fly   837 FINVVQI---KLSDHF------KMASAK----------------VGATIGMNMTSELGDEGGSQV 876
            .:::..|   ||  ||      .:|:.:                ||..||::.......:..:.|
Worm   282 ALDIGSIYVRKL--HFIGKKIKNIANIRIWFGARNLEVRELITAVGQNIGIDQNVIADIDIDTLV 344

  Fly   877 KTPSELASVHGSRLDRIEEDGQEANGNGHSPVPPL 911
            ||..:   |...||.|:.:......|.....:.||
Worm   345 KTAIQ---VKLGRLSRVPQTHMIVEGIWPPELVPL 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34396	NP_611547.2	RILP-like	135..>217	CDD:304877
		Ion_trans_2	<614..670	CDD:285168	20/55 (36%)
		Ion_trans_2	771..847	CDD:285168	21/78 (27%)
twk-29	NP_001021467.1	Ion_trans_2	127..186	CDD:285168	20/65 (31%)
twk-29	NP_001021467.1	Ion_trans_2	216..292	CDD:285168	19/75 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D542195at33208
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920