Protein Alignment CG34396 and twk-36

DIOPT Version :10

• Sequence 1: NP_611547.2
• Gene: CG34396 / 37398
• FlyBaseID: FBgn0085425
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: NP_507485.2
• Gene: twk-36 / 180164
• WormBaseID: WBGene00006688
• Length: 562
• Species: Caenorhabditis elegans
• Alignment Length: 663
• Identity: 152/663 - (22%)
• Similarity: 248/663 - (37%)
• Gaps: 190/663 - (28%)

  Fly   344 QSELMQKYMEAAERAAKAEAALA----------EQILTAEGVRRSHSLRLADKEEKPQKRSSSLE 398
            :|.|.|||  ..||....:..|.          ..:||..|.|.:.|..|      |.:||:|::
 Worm    11 KSILSQKY--TVERKDTVQHVLEGPGLSRNQSNASVLTLPGSRNTSSNHL------PAQRSTSVD 67

  Fly   399 RPLRPK--------RSGSLERKEQVTQELLEG--TTTNEADTEPKSLGDQPLLPEESISEAKPKV 453
            ...|.:        :|...|.:..::|...:.  |.|...:|..|       || .:||..:.:|
 Worm    68 EVARHRVTYEMDAGKSEKSENQNPISQYYQKNHYTVTGNQETYQK-------LP-RNISANRFQV 124

  Fly   454 TLWQRLKNLFRRKKKIQAKGEDVTDLSTELPL---EKLASRGLLYSFSLEARHEWKRLKLDYPQK 515
            .           |..|..|.........|:|:   |:...:    ||...|.|. |:..|.|
 Worm   125 D-----------KASISQKSAPRASEPMEMPMLPQERQFDK----SFYWFAMHR-KKFGLRY--- 170

  Fly   516 VKELRQLRNRCIAYLICMAMLLGFGGLLFRYTEGAAENIYKCEVRKVKRD-FIDRLWDVSHNMRE 579
                       ||.|:...:....|..:|...||:.|. .:..||:...| .:|.|..|......
 Worm   171 -----------IALLVLALIYTLLGATVFYLIEGSNEK-SRLHVREQNLDKLLDELATVLSEAVN 223

  Fly   580 EDWKSLARQKLRSFEDELNNLAELGLRR--------------YPGQKSWNFVNCFIFCWTVITTI 630
            :..:|...|:::.|..|    :.:.|::              :|....|.|.:.|.|...|.||.
 Worm   224 DPEQSSEHQRMKEFIKE----SYISLQKHEEQYKWSTYYRLEHPDNLKWTFSSAFFFSMNVYTTT 284

  Fly   631 GYGHITPKTGMGRSLTIVYAIIGIPMFLIVLADLGKLFTRCVKFLWVYVRRMYYTRSCRRIRKQQ 695
            |||.|:.:|..|:..|::||...:|:.|::|.|||::|  .|.|..:|...:   .:.||||.::
 Worm   285 GYGSISAQTFSGQLFTMIYAFCFVPVTLVILRDLGQMF--LVNFTKLYAHGL---TAVRRIRGKR 344

  Fly   696 QIRSAMTGFNTMYDMAIRRPSMFFSNSAPENDEESQADAEAARSVGTSHPETPTSPYPETFEVDD 760
            ::                             ||                              |:
 Worm   345 EV-----------------------------DE------------------------------DE 350

  Fly   761 EFNLPVSVASLLLITYILL-GSFGFL---MMEPSWTP----LDAFYYVFISMSTIGFGDLVPSN- 816
            ...||:.....:||.|:|| .:|.:|   :|.|.|..    ..|||:.|||::|||.||::|:|
 Worm   351 IIQLPIKFCMTILIAYLLLCTTFVYLYDAVMGPEWDDGLPYFTAFYFSFISLTTIGLGDVMPNNV 415

  Fly   817 PFYVMVSMIYLMFGLALTSMFINVVQIKLSDH----FKMASAKVGATIGMNMTSELGDEGGSQVK 877
            |:...||||:.: |:|:|.:......|.:.:.    ..:|..|:         |.|..|....||
 Worm   416 PYAPPVSMIFFI-GMAVTKVVNRATFIAVENGVFGLMTLAETKI---------SMLLTERKPGVK 470

  Fly   878 TPSELASVHGSRLDRIEE------DGQEANGNGHSPVPPL------TSILRAPRPLSPASNGVDA 930
            |....:|  ||..:.::.      ||...:|:....:...      |..:|:......:::.|..
 Worm   471 TVRSTSS--GSSAESVDSKEPRGFDGDSDSGSDDGVINRRRNEMMNTFTVRSIATFMRSNHDVYG 533

  Fly   931 NGVGADAVGAGDV 943
            .|.|...:..||:
 Worm   534 GGFGRVQLRRGDL 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34396	NP_611547.2	Caldesmon	<64..>243	CDD:460421
		Ion_trans_2	<613..670	CDD:462301	23/56 (41%)
		Ion_trans_2	771..847	CDD:462301	32/84 (38%)
twk-36	NP_507485.2	Ion_trans_2	256..322	CDD:462301	23/65 (35%)
		Ion_trans_2	361..432	CDD:462301	30/71 (42%)