DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34396 and Kcnk7

DIOPT Version :9

Sequence 1:	NP_611547.2	Gene:	CG34396 / 37398	FlyBaseID:	FBgn0085425	Length:	975	Species:	Drosophila melanogaster
Sequence 2:	NP_034739.2	Gene:	Kcnk7 / 16530	MGIID:	1341841	Length:	343	Species:	Mus musculus

Alignment Length:	438	Identity:	91/438 - (20%)
Similarity:	156/438 - (35%)	Gaps:	130/438 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   530 LICMAMLL--GFGGLLFRYTEGAAENIYKCEVRKVKRDFIDRLWDVSHN--MREEDWKSLARQKL 590
            |:.||.||  |.|.::.:..||......:.:|:.....|     ...|.  :..|..:.|....|
Mouse    12 LLLMAHLLAMGLGAVVLQALEGPPARHLQAQVQAELASF-----QAEHRACLPPEALEELLGAVL 71

  Fly   591 RSFEDELNNLAELGLRRYPGQKSWNFVNCFIFCWTVITTIGYGHITPKTGMGRSLTIVYAIIGIP 655
            |:   :.:.::.||  ......:|:..:..:|..:::||.||||:.|.:..|::..:|||.:|:|
Mouse    72 RA---QAHGVSSLG--NSSETSNWDLPSALLFTASILTTTGYGHMAPLSSGGKAFCVVYAALGLP 131

  Fly   656 MFLIVLADLG----KLFTRCVKFLWVYVRRMYYTRSCRRIRKQQQIRSAMTGFNTMYDMAIRRPS 716
            ..|.::|.|.    .:|:|...  ||.:|                           :.:|
Mouse   132 ASLALVAALRHCLLPVFSRPGD--WVAIR---------------------------WQLA----- 162

  Fly   717 MFFSNSAPENDEESQADAEAARSVGTSHPETPTSPYPETFEVDDEFNLPVSVASLLLITYILLGS 781
                          .|.|...::.|                    ..|.|:...:||...:|.|.
Mouse   163 --------------PAQAALLQAAG--------------------LGLLVACVFMLLPALVLWGV 193

  Fly   782 FGFLMMEPSWTPLDAFYYVFISMSTIGFGDLVPSNPFYVMVSMIYLMFGLALTSMFINVVQIKLS 846
            .|...:      |:|.|:.|.|:||||.|||:|::             |..|.....::.|..|.
Mouse   194 QGDCSL------LEAIYFCFGSLSTIGLGDLLPAH-------------GRGLHPAIYHLGQFALL 239

  Fly   847 DHFKMASAKVGATIGMNMTSELGDEGGSQVKTPSELASVHGSRLDRIEEDG-------------Q 898
            .:..:  ..:...:.:...|||     .||:...:.....|||.|. ::||             .
Mouse   240 GYLLL--GLLAMLLAVETFSEL-----PQVRAMVKFFGPSGSRTDE-DQDGILGQDELALSTVLP 296

  Fly   899 EANGNGHSPVPPLTSILRAPRPLSPASNGVDANGVGADAVGAGDVTPP 946
            :|...|.:....::.....|:|..|:    .|.|...|.||..:...|
Mouse   297 DAPVLGPTTPASVSEHQNRPQPADPS----QATGSQLDRVGGPEREAP 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34396	NP_611547.2	RILP-like	135..>217	CDD:304877
		Ion_trans_2	<614..670	CDD:285168	19/59 (32%)
		Ion_trans_2	771..847	CDD:285168	22/75 (29%)
Kcnk7	NP_034739.2	Ion_trans_2	<89..140	CDD:285168	17/50 (34%)
Kcnk7	NP_034739.2	Ion_trans_2	178..>225	CDD:285168	20/65 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845636
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.830