DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34396 and kcnk17

DIOPT Version :9

Sequence 1:	NP_611547.2	Gene:	CG34396 / 37398	FlyBaseID:	FBgn0085425	Length:	975	Species:	Drosophila melanogaster
Sequence 2:	XP_005158968.1	Gene:	kcnk17 / 101882139	ZFINID:	ZDB-GENE-120113-3	Length:	299	Species:	Danio rerio

Alignment Length:	361	Identity:	86/361 - (23%)
Similarity:	146/361 - (40%)	Gaps:	99/361 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   527 IAYLICMAMLLGFGGLLFRYTEGAAENIYKCEVRKVKR-DFIDRLWDVSHNMREEDWKSLARQKL 590
            :||::       .|||:|...||... :.:..:.|.|| :.:::...:..|...|..:.:....|
Zfish    29 VAYVL-------VGGLVFWKLEGWYV-LQQIALLKEKRLELLEKYPCLGQNGLSELAQMIKSASL 85

  Fly   591 RSFEDELNNLAELGLRRYPGQKSWNFVNCFIFCWTVITTIGYGHITPKTGMGRSLTIVYAIIGIP 655
            .....:.|:.|: ||        |.|.:..:|..||:||||||:|.|.|..|:...:::|:.|||
Zfish    86 SGLSPDSNDTAD-GL--------WKFTSSSVFAATVVTTIGYGNIVPLTTAGQIFCVMFALFGIP 141

  Fly   656 MFLIVLADLGKLFTRCVKFLWVYVRRMYYTRSCRRIRKQQQIRSAMTGFNTMYDMAIRRPSMFFS 720
            :.::||..:||                                         |.:||.|   .|.
Zfish   142 LNVVVLNRVGK-----------------------------------------YMLAIER---HFC 162

  Fly   721 NSAPENDEESQADAEAARSVGTSHPETPTSPYPETFEVDDEFNLPVSVASLLLITYILLGSFGFL 785
            |...:..:..:....:..|:..                       ||.|.|.|:..:||    |.
Zfish   163 NFLEKKIDRGKCVRISIHSISF-----------------------VSSAFLYLVVPMLL----FK 200

  Fly   786 MMEPSWTPLDAFYYVFISMSTIGFGDLVPS-NP------FYVMVSMIYLMFGLALTSMFIN-VVQ 842
            ..| .|:..:|.||.||::|||||||.|.. ||      :|..:..:::.||||..::.:| .:.
Zfish   201 EYE-GWSYAEAIYYCFITLSTIGFGDYVADHNPEINYPEWYSCLMAVWIFFGLAWLALLVNHTID 264

  Fly   843 IKLSDHFKMASAKVGATIGMNMTSELGDEGGSQVKT 878
            :..|.:..:...:.|.: ..|.|.|..::|..:.:|
Zfish   265 LLESLNAYLRGRQTGQS-QTNETEEKPEKGLKEEET 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34396	NP_611547.2	RILP-like	135..>217	CDD:304877
		Ion_trans_2	<614..670	CDD:285168	23/55 (42%)
		Ion_trans_2	771..847	CDD:285168	28/83 (34%)
kcnk17	XP_005158968.1	Ion_trans_2	<100..154	CDD:285168	23/94 (24%)
kcnk17	XP_005158968.1	Ion_trans_2	189..267	CDD:285168	28/82 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910