DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34396 and kcnk2

DIOPT Version :9

Sequence 1:	NP_611547.2	Gene:	CG34396 / 37398	FlyBaseID:	FBgn0085425	Length:	975	Species:	Drosophila melanogaster
Sequence 2:	XP_031758740.1	Gene:	kcnk2 / 100495685	XenbaseID:	XB-GENE-952207	Length:	412	Species:	Xenopus tropicalis

Alignment Length:	366	Identity:	84/366 - (22%)
Similarity:	141/366 - (38%)	Gaps:	119/366 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   529 YLICMAMLLGFGGLLFRYTEGAAENIYKCEVRKVKRDFIDRLWDVSH---NMREEDWKSLARQKL 590
            :|:.:..|: .|..:|:..|...|:..:..:...|.:||     ::|   |:.|.|  .|.:|.:
Frog    52 FLVVVLYLI-IGATVFKALEQPHESAQRTTIVIQKNNFI-----LNHSCVNVTELD--ELIQQLM 108

  Fly   591 RSFEDELNNLAELGLRRYPGQKS-WNFVNCFIFCWTVITTIGYGHITPKTGMGRSLTIVYAIIGI 654
            .:.     |...:.:.....|.| |:..:.|.|..|||||||:|:|:|:|..|:...|:||::||
Frog   109 AAI-----NAGIIPIGNTSHQNSHWDLGSSFFFAGTVITTIGFGNISPRTKGGKIFCIIYALLGI 168

  Fly   655 PMFLIVLADLGKLFTRCVKFLWVYVRRMYYTRSCRRIRKQQQIRSAMTGFNTMYDMAIRRPSMFF 719
            |:|..:||.:|                             .|:       .|::...|.|....|
Frog   169 PLFGFLLAGVG-----------------------------DQL-------GTIFGKGIARVEDMF 197

  Fly   720 SNSAPENDEESQADAEAARSVGTSHPETPTSPYPETFEVDDEFNLPVSVASLLLITYILLGSFGF 784
                    |:........|.:.|                               :.:||.|...|
Frog   198 --------EKWNVSQTKIRIIST-------------------------------VIFILFGCILF 223

  Fly   785 LMME-------PSWTPLDAFYYVFISMSTIGFGDLVPSN------PFYVMVSMIYLMFGLALTSM 836
            :.:.       ..|..|||||:|.|:::||||||.|...      .||..|...:::.|||..:.
Frog   224 VAIPAVIFQHIEDWHTLDAFYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAA 288

  Fly   837 FINVVQIKLSDHFKMASAKVGATIG----------MNMTSE 867
            .::::    ||..::.|.|....:|          .|:|:|
Frog   289 VLSMI----SDWLRVISRKTKEEVGEFRAHAAEWTANVTAE 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34396	NP_611547.2	RILP-like	135..>217	CDD:304877
		Ion_trans_2	<614..670	CDD:285168	25/55 (45%)
		Ion_trans_2	771..847	CDD:285168	25/88 (28%)
kcnk2	XP_031758740.1	Ion_trans_2	<128..182	CDD:400301	25/82 (30%)
kcnk2	XP_031758740.1	Ion_trans_2	220..298	CDD:400301	24/81 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000