DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34396 and kcnk4

DIOPT Version :9

Sequence 1:	NP_611547.2	Gene:	CG34396 / 37398	FlyBaseID:	FBgn0085425	Length:	975	Species:	Drosophila melanogaster
Sequence 2:	XP_002940275.1	Gene:	kcnk4 / 100488063	XenbaseID:	XB-GENE-994204	Length:	430	Species:	Xenopus tropicalis

Alignment Length:	507	Identity:	111/507 - (21%)
Similarity:	186/507 - (36%)	Gaps:	154/507 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   530 LICMAMLLGF---GGLLFRYTEGAAENIYKCEVRKVKRDFIDRLWDVSHNMREED----WKSLAR 587
            |....::||:   |.::|:..|...|.:.:.::.:.:|.|:|     .|...:||    :....:
Frog     7 LALFGVVLGYLVTGAVVFQMLEQPFEALKQSQLNEHRRAFLD-----EHICLQEDRLDEFIEQVK 66

  Fly   588 QKLRSFEDELNNLAELGLRRYPGQKSWNFVNCFIFCWTVITTIGYGHITPKTGMGRSLTIVYAII 652
            :.:.|..|...|...:..|       |:..:||.|..|:|||||||:..|||..|:...|.||::
Frog    67 EAIGSGVDPSANATNVTTR-------WDIGSCFFFAGTIITTIGYGNNAPKTDGGQIFCIFYALV 124

  Fly   653 GIPMFLIVLADLGKLFTRCVKFLWVYVRRMYYTRSCRRIRKQQQIRSAMTGFNTMYDMAIRRPSM 717
            |||:|.|:||.:|.                :...|.|:                    .|.:..|
Frog   125 GIPLFGILLAGVGD----------------HLGSSLRK--------------------GIGKVEM 153

  Fly   718 FFSNSAPENDEESQADAEAARSVGTSHPETPTSPYPETFEVDDEFNLPVSVASLLLITYILLGSF 782
            .|.        :....|...|.:...                    |.:.:..||   ::|:..|
Frog   154 LFL--------KWHVSATIVRVISAL--------------------LFILIGCLL---FVLIPMF 187

  Fly   783 GFLMMEPSWTPLDAFYYVFISMSTIGFGDLV-------------PSNPFYVMVSMIYLMFGLALT 834
            .|..:| :||.|::.|:|.|:::|.||||.|             |...|::::.:.|....|.:.
Frog   188 IFQKIE-NWTLLESIYFVVITLTTTGFGDYVAGDGAGHEHTWYKPVVWFWILLGLAYFASILTMI 251

  Fly   835 SMFINVVQIK-------LSDHFKMASAKVGAT-------IGMNMTSELGDEGGSQVKTPSELASV 885
            ..::.|:..|       |:.|....:|.:.|.       :.:|....|..:.|.......|...|
Frog   252 GNWLRVLTRKTRAEMGGLTAHAANWTASMTADMKLPHRGLSLNFQERLKTQKGGMRAPGQEQVDV 316

  Fly   886 HGSRLDRIEEDGQEANGNGH------SPVPPLTSILRAPRPLSP--------------------- 923
            .|...::.||:.:|......      ||.||   |::...|:||
Frog   317 EGEDEEQEEEEEEEREEEDKDPPHILSPSPP---IVKQTSPVSPPMKTEDMEIKALEWGANMAFI 378

  Fly   924 --ASNGVDANGVG---ADAVGAGDVTPPPLLPRRQVSVD----PQPPAEGEN 966
              :|:.....|.|   .:.||... ||.....||.|..|    |:...:||:
Frog   379 DESSDSQSEKGEGEKRVERVGRAR-TPRGRRKRRGVKGDSHQFPRNRDKGES 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34396	NP_611547.2	RILP-like	135..>217	CDD:304877
		Ion_trans_2	<614..670	CDD:285168	27/55 (49%)
		Ion_trans_2	771..847	CDD:285168	25/95 (26%)
kcnk4	XP_002940275.1	Ion_trans_2	<85..138	CDD:285168	27/59 (46%)
kcnk4	XP_002940275.1	Ion_trans_2	178..256	CDD:285168	22/81 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000