Protein Alignment Rbpn-5 and PIB2

DIOPT Version :10

• Sequence 1: NP_611545.1
• Gene: Rbpn-5 / 37395
• FlyBaseID: FBgn0034585
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_011492.3
• Gene: PIB2 / 852861
• SGDID: S000002991
• Length: 635
• Species: Saccharomyces cerevisiae
• Alignment Length: 473
• Identity: 88/473 - (18%)
• Similarity: 169/473 - (35%)
• Gaps: 86/473 - (18%)

  Fly   155 IAPQVLNQVKKTLGSVRKLGTDSLNSSFQQDEDTRASSKGNGKQYAPEEAEMMHSIVEQLQEEMK 219
            |||:.....::::  :..:...|:.:..:|.:..:.||.|.|..:.
Yeast    62 IAPRASTHSEQSI--LSSISLKSMVNQHRQQQLQQESSTGAGTGFV------------------- 105

  Fly   220 ALKVKLREQDEQLQAKSASDESALHKSTSMDVAESACESCSLAE--------KKTEELGAHI--- 273
                     |.:.|.:|.:..|.|.|:::.:...|: .|..|.|        ..::|:|..:
Yeast   106 ---------DRKQQIQSPAMVSILRKNSAEENVRSS-HSSKLGEGQIDGRKASASKEIGKTLPFT 160

  Fly   274 --NKQQKQVDLLQKQLVESRETLVKEAALRKDLEDQWQEKREAHKSEV--QSLRD------QAKT 328
              .:...::|.....:..||....|...:..:|||...:..|..:..:  |:||.      .|.:
Yeast   161 DDQRSNPELDPTNSVVDVSRGKNTKSKTVFNELEDDADDDDEVRQKNLTTQALRKLSSFKMNASS 225

  Fly   329 NEQRLLDMQQKFLETKDEVIKQIQRVSDDRERVNKQLETLQADNDFLSGRYLATSEEIDNQYINL 393
            |.:  |..:.|..|:.......:.  |....:|...::.|...|          |..:.......
Yeast   226 NLR--LSKENKAKESSSSSTSSVS--SSSTSKVENIVDKLTTTN----------SSSMSQLRFGN 276

  Fly   394 PNTVVELQELILRQQSELIQARVSSEYERQKCTSTEDEIQILRAQLEESNNERRAYKRKMQLDIK 458
            .|.:::......:...:.:..:.|.|:..|..:||.....    ..:..:|.|:....|..|.|.
Yeast   277 TNVIIDSVNHAAKPPHQQMLRKPSLEFLPQPASSTNLNFN----SNKHKSNVRQISNPKKPLYIP 337

  Fly   459 SLQDRVTE-HLVTVQAYETTKTQLERKEAELNKQLSECRVEIIELQEAN-------EKYAKTNA- 514
            ::..:|:| ::........|.:...:|.:.|....:..:.:...:|.||       :...::|.
Yeast   338 AVLRKVSETNITNDDLLNATLSSYYKKASNLEHGFNPSKSQSASVQNANNLRIISSQSSVQSNTS 402

  Fly   515 ----DYKTKIKTLQEELSTMETVQKDFVKLSQTLQMSLEELRHADTEVRWQDDDDVNNCPTCNAY 575
                .||.||.:.   |........|.:.|..|:........:..|:..|..|...|:|..|:..
Yeast   403 SILESYKNKISSY---LFPNSIPNSDRINLIPTISNRNSARVNPPTKDHWIPDSKRNSCRYCHKP 464

  Fly   576 FTVMVRKIHCRHCGHIYC 593
            ||:..||.||||||.|:|
Yeast   465 FTLWERKHHCRHCGDIFC 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rbpn-5	NP_611545.1	Rabaptin	22..>374	CDD:367545	41/239 (17%)
		Rab5-bind	256..555	CDD:462752	54/332 (16%)
		FYVE_RABE_unchar	557..629	CDD:277278	17/37 (46%)
PIB2	NP_011492.3	FYVE	446..530	CDD:214499	17/37 (46%)