Protein Alignment Rbpn-5 and Rabep2

DIOPT Version :10

• Sequence 1: NP_611545.1
• Gene: Rbpn-5 / 37395
• FlyBaseID: FBgn0034585
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_085074.2
• Gene: Rabep2 / 80754
• RGDID: 621416
• Length: 554
• Species: Rattus norvegicus
• Alignment Length: 587
• Identity: 140/587 - (23%)
• Similarity: 255/587 - (43%)
• Gaps: 150/587 - (25%)

  Fly    56 QKEA-EVSQSQQERRQLQAELDELKTHLMVADLKSQNELQ---LRDLKAQEEISSLQQLVQDTIE 116
            ||:| |.|:..:.|.:|...|.|::|...||::....:.:   ....:.|||::|||.:::|:|
  Rat    18 QKDASESSELSRLRAELAGALAEMETMKAVAEVSESTKAEAVAAVQRQCQEEVASLQAILKDSI- 81

  Fly   117 ETAHYKGEVERLRLELGKYQQIQQQTMAQQPQAESSGGIAPQVLNQVKKTLGSVRKLGTDSLNSS 181
              :.|:.::..|     |.::.|||..:::.:.|         |..:|:.|.....|  |||...
  Rat    82 --SSYETQIAAL-----KQERQQQQQDSEEKERE---------LGHLKQLLARAHPL--DSLEKQ 128

  Fly   182 FQQDEDTRASSKGNGKQYAPEEAEMMHSIVEQLQEEMKALKVKLREQDEQLQ--AKSASDESALH 244
            .::               |.|::|.:..||..:::|:..|||||...:|.:|  .:.....::||
  Rat   129 MEK---------------AHEDSEKLREIVLPMEQEIAELKVKLLRAEELIQEIQRRPRQPASLH 178

  Fly   245 KSTSM----------------------DVAESACESC--------------------------SL 261
            .||.:                      ..||:...:|                          |.
  Rat   179 GSTELLPLSRNPSPPLEPSEEPSGDAGPAAEAFAHNCDDSASISSFSLGGAAGSVSLRGPQGLSP 243

  Fly   262 AEKKTEEL---------GAHI---------NKQQKQVDLLQKQLVESRETLVKEAALRKDLEDQW 308
            .:::|..|         |.::         :.|.:|:.:..:||.:..|::.:|   |.:|::..
  Rat   244 EQEETASLVSTGTLVPEGIYLPPPGYQLVPDSQWEQLQVEGRQLQKELESVRRE---RDELQEGL 305

  Fly   309 QEKREAHKSEVQSLRDQAKTNEQRLLDMQQKFLETKDEVIKQIQRVSDDRERVNKQLETLQADND 373
            ....|....::|.|..|.:.:||.|..:|....:.::.|.:|:..::...:.::::::.|..:|.
  Rat   306 SRSNEDCAKQMQVLLAQVQNSEQLLRTLQGIVSQAQERVQRQMAELATSHKCLSQEVKRLNEENR 370

  Fly   374 FLSGRYLAT-----SEEIDNQYINLPNTVVELQELI--LRQQSELIQARVSSEYERQKCTSTEDE 431
            .|....|.:     ||:.::|...||:::.||.:|:  .|||:...|.....|.||.:
  Rat   371 GLRAEQLPSSALQGSEQQEDQDEALPSSIQELHQLVRHTRQQARARQQAQEHEAERLR------- 428

  Fly   432 IQILRAQLEESNNERRAYKRKM--QLDIKSLQDRVTEHLVTVQAYETTKTQLERKEAELNKQLSE 494
            |:|::  |.|:.:|..|.|..:  ||.::..:..|.|..:.....||.:.|.|..:|:|...|||
  Rat   429 IEIVK--LREALDEETAAKASLEGQLRVQREETDVLEASLCSLRIETERVQQEHHKAQLTDLLSE 491

  Fly   495 CRVEIIELQEANEKYAKTNADYKTKIKTLQEELSTMETVQKDFVKLSQTLQMSLEELRHADT--E 557
            .|.:.:.                     ||.||.|.|.||:|||:|||.||:.||::|.|||  :
  Rat   492 QRAKALR---------------------LQAELETSEQVQRDFVRLSQALQVRLEQIRQADTLEQ 535

  Fly   558 VR 559
            ||
  Rat   536 VR 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rbpn-5	NP_611545.1	Rabaptin	22..>374	CDD:367545	78/389 (20%)
		Rab5-bind	256..555	CDD:462752	82/351 (23%)
		FYVE_RABE_unchar	557..629	CDD:277278	2/3 (67%)
Rabep2	NP_085074.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29		5/10 (50%)
		Rabaptin	26..>168	CDD:367545	42/175 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	167..250		9/82 (11%)
		Rab5-bind	276..531	CDD:462752	77/287 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	375..395		4/19 (21%)