DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10527 and CG10916

DIOPT Version :9

Sequence 1:	NP_611544.1	Gene:	CG10527 / 37393	FlyBaseID:	FBgn0034583	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	NP_001261070.1	Gene:	CG10916 / 37081	FlyBaseID:	FBgn0034312	Length:	263	Species:	Drosophila melanogaster

Alignment Length:	153	Identity:	44/153 - (28%)
Similarity:	67/153 - (43%)	Gaps:	22/153 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 WVP-------AANGEVPP-NALE-GGFDSSEQLYIARARHEGDLIPGKLHPSHGVTYVAWGGGEH 214
            |||       ..:..:|| .|:: |..:.....|:||..:..||:|....|.....:     |.|
  Fly   107 WVPIDLDRDSLPDAHLPPEGAVQCGTNEDGLPTYVARGYYHDDLLPAPYVPEKKAAF-----GSH 166

  Fly   215 G--------HAEYEVLCAGGGQWLPVDAGNIPPNALPAGETAEGEPLFIGRATHDGTITVGKVQP 271
            .        ..|..||.....:|:|...|..|.:||..|.:..||..:.||..:.|.:.:|||.|
  Fly   167 SCSARTLTDDVEILVLNDCDYKWVPGQHGTYPRDALNTGYSELGEVTYTGRGLYQGILRLGKVHP 231

  Fly   272 SHGCCYIPYGGEELAYKEFEIYV 294
            ||...|||:.|:|::...:|:.|
  Fly   232 SHKVMYIPHHGQEVSVNTYEVLV 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10527	NP_611544.1	Methyltransf_FA	35..133	CDD:289052
		DM9	156..225	CDD:128937	19/82 (23%)
		DUF3421	180..286	CDD:288732	35/113 (31%)
		DM9	226..296	CDD:128937	25/69 (36%)
CG10916	NP_001261070.1	zf-RING_2	32..74	CDD:290367
		zf-rbx1	<32..74	CDD:289448
		DM9	105..183	CDD:128937	18/80 (23%)
		DUF3421	133..246	CDD:288732	35/117 (30%)
		DM9	186..254	CDD:128937	24/67 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449342
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR31649
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940