DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10527 and CG44251

DIOPT Version :9

Sequence 1:	NP_611544.1	Gene:	CG10527 / 37393	FlyBaseID:	FBgn0034583	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	NP_725246.1	Gene:	CG44251 / 36429	FlyBaseID:	FBgn0265186	Length:	478	Species:	Drosophila melanogaster

Alignment Length:	318	Identity:	93/318 - (29%)
Similarity:	131/318 - (41%)	Gaps:	82/318 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PIEVNTPDKLEYQFFPASGGVFTFKVRSPKDAHLALTPAPEENGPIFEIFLGGWENTKSVIRKDR 66
            |....|||.:     |..|||..  :.||       ||.|...|               |:...|
  Fly   203 PAYTPTPDPM-----PPVGGVMV--MPSP-------TPPPPAGG---------------VLVMPR 238

  Fly    67 QKP---------------------EVAEVPTPGILDAGEFRGFWVRWYDNVITVGREGDAAAFLS 110
            ..|                     |||  |.|..:.| |....      :|........|:.:..
  Fly   239 PPPPPPPAGGVLVMPPPPPSFTPAEVA--PPPSFVPA-EVTAV------SVPVAPSFTPASTYNP 294

  Fly   111 YDAGSLFPVNFVGICTGWGASGTWLIDEPAPSA-PVMGFAAPTGSGPGCWVPAANG-EVPPNALE 173
            |:||          |:.:..:     :..|||| ...|:    |:....||.|..| ...|:|:.
  Fly   295 YEAG----------CSSYTPA-----ECAAPSAYDAYGY----GNNYDVWVSAEPGYYYSPDAVI 340

  Fly   174 GGFDSS-EQLYIARARHEGDLIPGKLHPSHGVTYVAWGGGEHGHAEYEVLCAGGG-QWLPVDAGN 236
            ||.||: |||.:.||.:.|..:|||..||.|..|:|.||.|.....|::|...|. .|:|...||
  Fly   341 GGHDSNMEQLLVCRAYYRGVHVPGKAIPSQGCGYIAHGGREIIEPSYQMLVGKGKYHWVPSYGGN 405

  Fly   237 IPPNALPAGETAEGEPLFIGRATHDGTITVGKVQPSHGCCYIPYGGEELAYKEFEIYV 294
            :||.|:.||.|..|.||:|||..:.|::|.|.::..:.|..||:||:|:....:|:.|
  Fly   406 VPPGAVVAGTTPGGAPLYIGRGHYCGSLTPGVIETYNRCLQIPFGGQEIRLSNYEVLV 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10527	NP_611544.1	Methyltransf_FA	35..133	CDD:289052	20/118 (17%)
		DM9	156..225	CDD:128937	29/70 (41%)
		DUF3421	180..286	CDD:288732	45/106 (42%)
		DM9	226..296	CDD:128937	28/70 (40%)
CG44251	NP_725246.1	DM9	3..73	CDD:128937
		DUF3421	24..134	CDD:288732
		DM9	74..144	CDD:128937
		DM9	322..393	CDD:128937	29/70 (41%)
		DUF3421	344..455	CDD:288732	47/110 (43%)
		DM9	396..464	CDD:128937	27/68 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449343
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1154851at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR31649
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950