DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10527 and CG32633

DIOPT Version :9

Sequence 1:	NP_611544.1	Gene:	CG10527 / 37393	FlyBaseID:	FBgn0034583	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	NP_001259517.1	Gene:	CG32633 / 326225	FlyBaseID:	FBgn0052633	Length:	285	Species:	Drosophila melanogaster

Alignment Length:	234	Identity:	80/234 - (34%)
Similarity:	111/234 - (47%)	Gaps:	40/234 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 EVAEVPTPGILDAGEFRGFWVRWYDNVITVGREGDAA---AFLSYDAGSL-----FPVNFVGICT 126
            |..||| ||                 .:.|||..|..   |...|.||||     .|
  Fly    81 ENGEVP-PG-----------------AVKVGRNVDGEYLYAGRGYHAGSLTMGKVHP-------- 119

  Fly   127 GWGASGTWLIDEPAPSAPVMGFAAPTGSGPGCWVPAANGEVPPNALEGGFDSS-EQLYIARARHE 190
               :.|...|  |..|..|..||......|..|:......:|..||..|.||: :.:|:.|....
  Fly   120 ---SHGCLYI--PYDSDEVKIFAYEVLCQPERWIDTTATNIPDGALVAGHDSNGDTIYVGRVFRN 179

  Fly   191 GDLIPGKLHPSHGVTYVAWGGGEHGHAEYEVLCAGGGQWLPVDAGNIPPNALPAGETAEGEPLFI 255
            |||:|.|:.|:.|..|.|:...||...:.:||...|.:|:|...||:.|.||.:|...:||||::
  Fly   180 GDLLPAKVVPAKGKAYAAYAQAEHELTDVQVLTGSGFRWVPASHGNVAPGALSSGPNVDGEPLYV 244

  Fly   256 GRATHDGTITVGKVQPSHGCCYIPYGGEELAYKEFEIYV 294
            |||.:..:::|||:.|||||.|||:||||:..:.:|:.|
  Fly   245 GRAIYCDSLSVGKIHPSHGCIYIPFGGEEVRLENYEVLV 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10527	NP_611544.1	Methyltransf_FA	35..133	CDD:289052	17/70 (24%)
		DM9	156..225	CDD:128937	23/69 (33%)
		DUF3421	180..286	CDD:288732	46/105 (44%)
		DM9	226..296	CDD:128937	33/69 (48%)
CG32633	NP_001259517.1	DM9	3..73	CDD:128937
		DUF3421	24..134	CDD:288732	21/83 (25%)
		DM9	74..142	CDD:128937	24/91 (26%)
		DUF3421	165..275	CDD:288732	48/109 (44%)
		DM9	215..284	CDD:128937	33/69 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449348
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28P3B
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1154851at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR31649
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940