DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10527 and AgaP_AGAP009604

DIOPT Version :9

Sequence 1:	NP_611544.1	Gene:	CG10527 / 37393	FlyBaseID:	FBgn0034583	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	XP_318631.4	Gene:	AgaP_AGAP009604 / 1278977	VectorBaseID:	AGAP009604	Length:	298	Species:	Anopheles gambiae

Alignment Length:	298	Identity:	195/298 - (65%)
Similarity:	234/298 - (78%)	Gaps:	9/298 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 IEVNTPDKLEYQFFPASGGVFTFKVRSPKDAHLALTPAPEENGPIFEIFLGGWENTKSVIRKDRQ 67
            ||:.|.|||||:|.||..||..||||:|.|||:|||..|||:.|:.|:|:|||:||||||||:|.
Mosquito     4 IELETEDKLEYRFVPAGNGVVNFKVRAPNDAHIALTTNPEESDPMLEVFIGGWKNTKSVIRKNRT 68

  Fly    68 KPEVAEVPTPGILDAGEFRGFWVRWYDNVITVGREGDAAAFLSYDAGSLFPVNFVGICTGWGASG 132
            ||:||||.||.||:||||||||:||.|||||||.||.|||||||:....||:|.||.||||||:|
Mosquito    69 KPDVAEVETPDILNAGEFRGFWIRWQDNVITVGNEGAAAAFLSYENPEPFPINCVGFCTGWGATG 133

  Fly   133 TWLIDEPA-----PSAPVMGFAAPTGSGPGCWVPAANGEVPPNALEGGFDSSEQLYIARARHEGD 192
            :||| |||     ||||..  ||.:..|..|||.|||||:||||:.||.| .|.:||.||:|||.
Mosquito   134 SWLI-EPASEQASPSAPTA--AALSAGGAACWVAAANGEIPPNAVVGGSD-GEDMYIGRAQHEGG 194

  Fly   193 LIPGKLHPSHGVTYVAWGGGEHGHAEYEVLCAGGGQWLPVDAGNIPPNALPAGETAEGEPLFIGR 257
            :||||:..||||.|:||||.|:..|||||||..||:::|....:|||.||||||:.:||||||||
Mosquito   195 IIPGKVVASHGVCYIAWGGAENPKAEYEVLCDFGGEFVPASGSDIPPTALPAGESEDGEPLFIGR 259

  Fly   258 ATHDGTITVGKVQPSHGCCYIPYGGEELAYKEFEIYVT 295
            .||:||:||||||||||.|||||||:|||:.|:||:|:
Mosquito   260 VTHEGTVTVGKVQPSHGVCYIPYGGQELAFAEYEIFVS 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10527	NP_611544.1	Methyltransf_FA	35..133	CDD:289052	68/97 (70%)
		DM9	156..225	CDD:128937	44/68 (65%)
		DUF3421	180..286	CDD:288732	71/105 (68%)
		DM9	226..296	CDD:128937	48/70 (69%)
AgaP_AGAP009604	XP_318631.4	Methyltransf_FA	36..133	CDD:289052	68/96 (71%)
		DM9	161..225	CDD:128937	42/64 (66%)
		DUF3421	179..288	CDD:288732	72/109 (66%)
		DM9	228..297	CDD:128937	47/68 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	167	1.000	Domainoid score	I7979
eggNOG	1	0.900	-	-		E1_28P3B
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H122602
Inparanoid	1	1.050	411	1.000	Inparanoid score	I3859
OMA	1	1.010	-	-		QHG27710
OrthoDB	1	1.010	-	-		D1154851at2759
OrthoFinder	1	1.000	-	-		FOG0019900
OrthoInspector	1	1.000	-	-		oto107201
Panther	1	1.100	-	-	LDO	PTHR31649
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X15489
TreeFam	1	0.960	-	-
	13	12.940