DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10527 and AgaP_AGAP006398

DIOPT Version :9

Sequence 1:	NP_611544.1	Gene:	CG10527 / 37393	FlyBaseID:	FBgn0034583	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	XP_316431.3	Gene:	AgaP_AGAP006398 / 1277009	VectorBaseID:	AGAP006398	Length:	290	Species:	Anopheles gambiae

Alignment Length:	313	Identity:	89/313 - (28%)
Similarity:	120/313 - (38%)	Gaps:	133/313 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 GF-WVRWYD-----------------NVITVGR---EGD----------AAAFLSYDAGSLFPVN 120
            || |:.|..                 :.|.:||   |||          .||::|::...:|..:
Mosquito     4 GFNWIPWTSHQGIPPAAVYGGNDQDGSPIYIGRAYHEGDQLPAKVIPSKQAAYVSHNGMEIFKTH 68

  Fly   121 FVGICTGWGASGTWLIDEPAPSAPVMGFAAPTGSGPGCWVPAANGEVPPNA-LEGGFDSSEQLYI 184
            | .:.||.|.:                           ||.:.||.||.|| |.|...:.|||||
Mosquito    69 F-EVLTGTGFT---------------------------WVSSGNGHVPANAVLAGNTTTGEQLYI 105

  Fly   185 ARARHEGDLIPGKLHPSHGVTYVAWGGGEHGHAEYEVL----------CAG-------------- 225
            .|..|||.|.|||:|.|||..|:.:||.|.....||||          |:.
Mosquito   106 GRTHHEGSLTPGKIHRSHGCLYIPFGGAEQSFLSYEVLVGQQRSNWQHCSAHAPMPPNAVLAGND 170

  Fly   226 -----------------------------------------------GGQ--WLPVDAGNIPPNA 241
                                                           |||  |:|...|::||||
Mosquito   171 SDGSPIYVGRTYHEGDQLPAKVLPSKQIAYVCHNGQEIPKHSFEVLTGGQVSWVPSGFGSVPPNA 235

  Fly   242 LPAGETAEGEPLFIGRATHDGTITVGKVQPSHGCCYIPYGGEELAYKEFEIYV 294
            :..|.|:.||.|:||||.:.|::|.||:.|||...||||||.|:..|.:|:.:
Mosquito   236 VFGGRTSSGEALYIGRAHYMGSLTPGKIHPSHQTLYIPYGGSEIPIKNYEVLI 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10527	NP_611544.1	Methyltransf_FA	35..133	CDD:289052	18/76 (24%)
		DM9	156..225	CDD:128937	36/79 (46%)
		DUF3421	180..286	CDD:288732	59/178 (33%)
		DM9	226..296	CDD:128937	35/71 (49%)
AgaP_AGAP006398	XP_316431.3	DM9	4..75	CDD:128937	16/71 (23%)
		DUF3421	26..136	CDD:288732	45/137 (33%)
		DM9	76..146	CDD:128937	36/96 (38%)
		DM9	151..219	CDD:128937	1/67 (1%)
		DUF3421	170..279	CDD:288732	32/108 (30%)
		DM9	222..288	CDD:128937	32/65 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1154851at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920