DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10527 and cpamd8

DIOPT Version :9

Sequence 1:	NP_611544.1	Gene:	CG10527 / 37393	FlyBaseID:	FBgn0034583	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	XP_002934416.1	Gene:	cpamd8 / 100491045	XenbaseID:	XB-GENE-985023	Length:	1827	Species:	Xenopus tropicalis

Alignment Length:	366	Identity:	82/366 - (22%)
Similarity:	126/366 - (34%)	Gaps:	130/366 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 IEVNTPDKLEYQFF--PASGGVFTFKVRSPKDAHLALTPAPEENGPIFEIFLGGWENTKSVIRKD 65
            |:::||:|.|||:.  |.....|...|::..|||:||:..|.:...:.||.:||.:|:::.|...
Frog   940 IQISTPNKFEYQYVQKPQRMTHFDLTVKAHNDAHIALSSGPHDMAEMIEIVIGGQQNSRTWISTS 1004

  Fly    66 RQKPEVAEVPTPGILDAGEFRGFWVRWYDNVITVG---REGDAAAFLSYDAGSLFPVNFVGICTG 127
            :....|:...|..:|...|||.||:.|.:.||.||   ...:.:..:.:.......|.|:|..||
Frog  1005 KMGDPVSSASTSSVLSWDEFRAFWISWKNGVIQVGYGIYSSNDSVIVEWTVDRQPDVKFIGFSTG 1069

  Fly   128 WGASGTWLI------DE--------PAPSAPVMGFAAPTGS------GP-------------GCW 159
            ||:.|.:.|      ||        ..|...:.|....|.|      ||             ||
Frog  1070 WGSMGEFKIWRKEETDENHNEAFTLGVPHNVIPGSERATASIIGDVMGPTVSNLDNLLRLPFGC- 1133

  Fly   160 VPAANGE-----VPPNA------------------------------------LEGGF------D 177
                 ||     ..||.                                    |:|.:      |
Frog  1134 -----GEQNMIHFAPNVFVLKYLQKTRQLCPEVESEAVDYLVQGYQRQLTYKRLDGSYSAFGERD 1193

  Fly   178 SSEQLYIAR------ARHEGDLI--PGKL---------HPSHGVTYVAWG--------GGEHGHA 217
            ||..:::..      |:..|.:.  ||:|         |.:...::.|.|        ||.||..
Frog  1194 SSGSMWLTAFVLKSFAQSRGFIFIDPGELSAAKDWIIQHQNKDGSFPAMGRILNKDIQGGNHGKI 1258

  Fly   218 EYEVLCAGGGQWLPVDAGNIPPNALPAGETAEGEPLFIGRA 258
            ......|..              .|..|.|:|.|.:.:.:|
Frog  1259 ALTAYVAAA--------------LLETGVTSEDERIAVSKA 1285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10527	NP_611544.1	Methyltransf_FA	35..133	CDD:289052	29/100 (29%)
		DM9	156..225	CDD:128937	24/153 (16%)
		DUF3421	180..286	CDD:288732	19/104 (18%)
		DM9	226..296	CDD:128937	6/33 (18%)
cpamd8	XP_002934416.1	MG1	22..>83	CDD:375333
		YfaS	<54..>257	CDD:225248
		MG4	339..>398	CDD:375332
		A2M_N_2	444..615	CDD:377903
		A2M	737..828	CDD:365945
		Methyltransf_FA	974..1075	CDD:371989	29/100 (29%)
		A2M_2	1119..1418	CDD:239227	30/187 (16%)
		A2M_recep	1556..1646	CDD:369460
		KAZAL	1700..1744	CDD:197624
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	65	1.000	Domainoid score	I9925
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000