DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht9 and chia.3

DIOPT Version :9

Sequence 1:	NP_611543.3	Gene:	Cht9 / 37392	FlyBaseID:	FBgn0034582	Length:	368	Species:	Drosophila melanogaster
Sequence 2:	NP_998378.1	Gene:	chia.3 / 406819	ZFINID:	ZDB-GENE-040426-2891	Length:	471	Species:	Danio rerio

Alignment Length:	393	Identity:	149/393 - (37%)
Similarity:	201/393 - (51%)	Gaps:	35/393 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKL---LALLAVLCLSQVIGAERIVNCYWGTWANYRSGNGKFDVSNIDAGLCTHLSYSFFGIND 62
            ||:|   ..|..|||   .:.....:.||:..|:.||.|.||:..:|:|..|||||.|:|..||.
Zfish     1 MGRLTLIAGLSLVLC---HVAFSMEMACYFTNWSQYRPGIGKYTPANVDPYLCTHLIYAFSIINQ 62

  Fly    63 NGEIQSLDTWLDYDL-GFINQAISLKNQNSNLKVLAVVGGWNEGSTKYSSMSGDWYKRQNFINSA 126
            ..|:.:.: |.|..| ...|:   |||:|..||.|..|||||.||.::|.|..:...|:.||.|.
Zfish    63 RNELVTYE-WNDETLYKAFNE---LKNKNPTLKTLLAVGGWNFGSAQFSIMVSNPANRKTFIQST 123

  Fly   127 LNLLRNHGFDGLDLDWEYPNQRGGNWNDRANFVTLLREIKEAFAPYGYELG-------IAVGAGE 184
            :..||.|||||||||||||..||....|:..|..|.:|:..|:.......|       .||.||:
Zfish   124 IKFLRTHGFDGLDLDWEYPGARGSPPEDKQRFTLLCKELVAAYEAESKATGNPQLMLTAAVSAGK 188

  Fly   185 SLASASYEIANIAQQVDFINVMTYDFAMASDGQTGFNAPQWA------------VENAINFWLSQ 237
            ......||||.||:.::|||||||||....:..||.|:|.:.            .:.|:.:|...
Zfish   189 GTIDDGYEIAEIAKYLNFINVMTYDFHGTWERFTGHNSPLYQGSKDEGDLIYFNTDYAMRYWRDN 253

  Fly   238 GAPANKLVLGVGTYGRSFQLSDSSQNWPGAPCRGEGSAGSYTGSTGYLGYNEICQNNWHTVFDY- 301
            |.|..||.:|...|||:|:|: ||....|||..|..|||:||...|:..|.|||.....|...:
Zfish   254 GTPVEKLRMGFAAYGRTFRLT-SSDTSVGAPASGPASAGTYTREAGFWSYYEICGFLEGTTIQWI 317

  Fly   302 -DNAAPYAYSGDQWVSFDNVLSVQYKMDFALSKGLAGAMIWSLETDDYRGQ-CGE-TYPLLKTIN 363
             |...|||....:||.||...|.:.|:.:...|...||.:|:|:.||:.|| |.: .:||:..:.
Zfish   318 DDQKVPYATKNSEWVGFDTKESYETKVRYLKDKNFGGAFVWALDLDDFAGQFCSQGNHPLMAHLR 382

  Fly   364 RKL 366
            ..|
Zfish   383 NLL 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht9	NP_611543.3	GH18_chitolectin_chitotriosidase	23..366	CDD:119351	141/366 (39%)
Cht9	NP_611543.3	Glyco_18	23..346	CDD:214753	134/344 (39%)
chia.3	NP_998378.1	Glyco_18	24..363	CDD:214753	134/343 (39%)
		GH18_chitolectin_chitotriosidase	25..385	CDD:119351	141/364 (39%)
		ChtBD2	421..469	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58170
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.830