DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht9 and chia.2

DIOPT Version :9

Sequence 1:	NP_611543.3	Gene:	Cht9 / 37392	FlyBaseID:	FBgn0034582	Length:	368	Species:	Drosophila melanogaster
Sequence 2:	NP_998414.1	Gene:	chia.2 / 406338	ZFINID:	ZDB-GENE-040426-2014	Length:	470	Species:	Danio rerio

Alignment Length:	390	Identity:	154/390 - (39%)
Similarity:	207/390 - (53%)	Gaps:	43/390 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKLLALLA----VLC---LSQVIGAERIVNCYWGTWANYRSGNGKFDVSNIDAGLCTHLSYSFF 58
            ||: |.|:|    |||   .|..:|      ||:..|:.||.|.||:..:|:|..|||||.|:|.
Zfish     1 MGR-LTLVAGLGLVLCHLAFSMEMG------CYFTNWSQYRPGIGKYTPANVDPFLCTHLFYAFA 58

  Fly    59 GINDNGEIQSLDTWLDYDL-GFINQAISLKNQNSNLKVLAVVGGWNEGSTKYSSMSGDWYKRQNF 122
            .||...|:.:.: |.|..| ...|:   |||.|.:|:.|..|||||.|||::|.|......||.|
Zfish    59 MINHANELITYE-WNDETLYKAFNE---LKNTNPHLRTLLAVGGWNFGSTQFSIMVSSAANRQTF 119

  Fly   123 INSALNLLRNHGFDGLDLDWEYPNQRGGNWNDRANFVTLLREIKEAFAPYGYELG-------IAV 180
            |.|::..||.:||||:|||||||..||....|:..|..|.:|:.||:...|...|       .||
Zfish   120 IQSSIKFLRTYGFDGMDLDWEYPGSRGSPPEDKQRFTLLCKELLEAYEAEGKATGRRRLMLSAAV 184

  Fly   181 GAGESLASASYEIANIAQQVDFINVMTYDFAMASDGQTGFNAPQWA------------VENAINF 233
            .||:......||||.||:.:||||:|||||....:..||.|:|.:.            .:.|:.:
Zfish   185 SAGKGTIDDGYEIAEIAKYLDFINIMTYDFHGTWERFTGHNSPLYQGSKDEGDLVYFNTDYAMRY 249

  Fly   234 WLSQGAPANKLVLGVGTYGRSFQLSDSSQNWPGAPCRGEGSAGSYTGSTGYLGYNEICQNNWHTV 298
            |...|.|..||.:|..||||:|:|: ||....|||..|..|||:||...|:..|.|||.....|.
Zfish   250 WRDNGTPVEKLRMGFATYGRTFRLT-SSDTSVGAPASGPASAGTYTREAGFWSYYEICGFLEGTT 313

  Fly   299 FDY--DNAAPYAYSGDQWVSFDNVLSVQYKMDFALSKGLAGAMIWSLETDDYRGQ-CGE-TYPLL 359
            ..:  |...|||....:||.||...|.:.|:.:...|...||.:|:|:.||:.|| ||: .:||:
Zfish   314 VQWIDDQKVPYATKNSEWVGFDTKESYETKVRYLKDKKFGGAFVWALDLDDFAGQFCGQGNHPLM 378

Fly 360 359
Zfish 379 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht9	NP_611543.3	GH18_chitolectin_chitotriosidase	23..366	CDD:119351	144/361 (40%)
Cht9	NP_611543.3	Glyco_18	23..346	CDD:214753	136/344 (40%)
chia.2	NP_998414.1	GH18_chitolectin_chitotriosidase	23..385	CDD:119351	145/367 (40%)
		Glyco_18	24..363	CDD:214753	137/349 (39%)
		CBM_14	423..468	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58170
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.930