DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht9 and chia.1

DIOPT Version :9

Sequence 1:	NP_611543.3	Gene:	Cht9 / 37392	FlyBaseID:	FBgn0034582	Length:	368	Species:	Drosophila melanogaster
Sequence 2:	NP_998215.1	Gene:	chia.1 / 406323	ZFINID:	ZDB-GENE-040426-1994	Length:	455	Species:	Danio rerio

Alignment Length:	390	Identity:	139/390 - (35%)
Similarity:	202/390 - (51%)	Gaps:	36/390 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LLALLAVLCLSQVIGAERIVNCYWGTWANYRSGNGKFDVSNIDAGLCTHLSYSFFGINDNGEIQS 68
            :||.|.:|...|::.:.::| ||...|:.||.|||||...|||..||||:.|:...|:.:.:|.:
Zfish     6 ILAGLGILLSLQIVSSTKLV-CYMTNWSQYRPGNGKFLPENIDPFLCTHVVYALATISYDNQITT 69

  Fly    69 LDTWLDYDLGFINQAISLKNQNSNLKVLAVVGGWNEGSTKYSSMSGDWYKRQNFINSALNLLRNH 133
            :: |.|.||  ......||..|..||....|||...|.:.|.:|......|:.||.:||..||.|
Zfish    70 IE-WNDVDL--YKSMNELKKVNPALKTQLSVGGLVNGVSPYINMVATPENRKAFIRNALLFLRLH 131

  Fly   134 GFDGLDLDWEYPNQRGGNWNDRANFVTLLREIKEAFAPYGYE-------LGIAVGAGESLASASY 191
            .|||:|:||:||...|....|:....|.::|:::|......:       |.|.|.|.::....:|
Zfish   132 EFDGMDIDWQYPGHNGSPPQDKQRLTTFIKEMRDAIEQEAIDTKKTPLLLSIKVSAIKTTIENAY 196

  Fly   192 EIANIAQQVDFINVMTYDFAMASDGQTGFNAPQWA------------VENAINFWLSQGAPANKL 244
            |...:|..|||:.:|:||:....|..||.|:|.:.            :.:::.|||..||||::|
Zfish   197 EAKEVASLVDFVTIMSYDYHGHWDPITGHNSPLFRSSFDTGSIVHHNINSSLEFWLGSGAPADRL 261

  Fly   245 VLGVGTYGRSFQLSDSSQNWPGAPCRGEGSAGSYTGSTGYLGYNEICQN------NWHTVFDYDN 303
            :||:.||||:|.|| :||...|||..|...||.||...|:..|.|||..      :|   .| :.
Zfish   262 LLGLPTYGRTFMLS-TSQTGLGAPANGPADAGPYTREAGFWSYYEICPMESSVPIHW---ID-EQ 321

  Fly   304 AAPYAYSGDQWVSFDNVLSVQYKMDFALSKGLAGAMIWSLETDDYRGQ-C-GETYPLLKTINRKL 366
            ..|||..|..||.|||..|:..|:.:..|..|.||.:|:|:.||:.|: | ...|||:..:...|
Zfish   322 MVPYAVQGRAWVGFDNQESITAKVQWLNSLKLGGASVWTLDFDDFAGRFCYNGAYPLVNHLRNSL 386

Fly 367 366
Zfish 387 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht9	NP_611543.3	GH18_chitolectin_chitotriosidase	23..366	CDD:119351	133/369 (36%)
Cht9	NP_611543.3	Glyco_18	23..346	CDD:214753	126/347 (36%)
chia.1	NP_998215.1	Glyco_18	23..364	CDD:214753	126/349 (36%)
		GH18_chitolectin_chitotriosidase	24..386	CDD:119351	133/370 (36%)
		ChtBD2	407..455	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592089
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58170
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.860