DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht9 and chia.6

DIOPT Version :9

Sequence 1:	NP_611543.3	Gene:	Cht9 / 37392	FlyBaseID:	FBgn0034582	Length:	368	Species:	Drosophila melanogaster
Sequence 2:	NP_955897.2	Gene:	chia.6 / 322420	ZFINID:	ZDB-GENE-030131-1140	Length:	480	Species:	Danio rerio

Alignment Length:	384	Identity:	158/384 - (41%)
Similarity:	212/384 - (55%)	Gaps:	40/384 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 GKLLALLAVLCLSQVIGAERIVNCYWGTWANYRSGNGKFDVSNIDAGLCTHLSYSFFGINDNGEI 66
            |..|||......||::       ||:..|:.||...||:..||:|..|||||.|:|..||:..::
Zfish     9 GFSLALCHFGLASQLV-------CYFTNWSQYRPDVGKYMPSNVDPHLCTHLIYAFSIINNENKL 66

  Fly    67 QSLDTWLDYDLGFINQAIS-LKNQNSNLKVLAVVGGWNEGSTKYSSMSGDWYKRQNFINSALNLL 130
            .:.: |.|..|   .|:.: ||..|.|||.|..|||||.|:|::|||......||.||.|::..|
Zfish    67 TTYE-WNDETL---YQSFNGLKQSNPNLKTLLAVGGWNFGTTQFSSMVSTPQNRQTFIQSSITFL 127

  Fly   131 RNHGFDGLDLDWEYPNQRGGNWNDRANFVTLLREIKEAFAPYGYELG-------IAVGAGESLAS 188
            |.|||||||||||||..||....|:..|..|.:|:.||:.......|       .||.||:....
Zfish   128 RTHGFDGLDLDWEYPGSRGSPPEDKQRFTLLCKELVEAYQAESAATGRPRLMLTAAVAAGKGNID 192

  Fly   189 ASYEIANIAQQVDFINVMTYDFAMASDGQTGFNAP------------QWAVENAINFWLSQGAPA 241
            |.||||.||:.:||||:|||||..:.:..||.|:|            .:..:.|:.:|..||||.
Zfish   193 AGYEIAEIAKYLDFINIMTYDFHGSWESVTGHNSPLYRGSGDIGDKIYYNTDFAMTYWRDQGAPV 257

  Fly   242 NKLVLGVGTYGRSFQLSDSSQNWPGAPCRGEGSAGSYTGSTGYLGYNEIC----QNNWHTVFDYD 302
            .||.:|...|||:|:|| |:.:..|||..|..|||:||...|:..|.|||    |.....:  .|
Zfish   258 EKLRMGFAAYGRTFRLS-SAVSGVGAPASGAASAGTYTREAGFWSYYEICTFLKQATVQQI--VD 319

  Fly   303 NAAPYAYSGDQWVSFDNVLSVQYKMDFALSKGLAGAMIWSLETDDYRGQ-CGET-YPLL 359
            ...|||..|.:||.|||:.|.:.|:|:...||..||.:|:|:.||:.|| ||:: |||:
Zfish   320 QKVPYATKGQEWVGFDNMESYKTKVDYLKEKGFGGAFVWALDLDDFSGQFCGQSKYPLI 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht9	NP_611543.3	GH18_chitolectin_chitotriosidase	23..366	CDD:119351	152/363 (42%)
Cht9	NP_611543.3	Glyco_18	23..346	CDD:214753	143/346 (41%)
chia.6	NP_955897.2	Glyco_18	22..363	CDD:214753	144/354 (41%)
		GH18_chitolectin_chitotriosidase	23..385	CDD:119351	152/370 (41%)
		CBM_14	433..479	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58170
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.830