DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht9 and Chit1

DIOPT Version :9

Sequence 1:	NP_611543.3	Gene:	Cht9 / 37392	FlyBaseID:	FBgn0034582	Length:	368	Species:	Drosophila melanogaster
Sequence 2:	NP_001073157.1	Gene:	Chit1 / 289032	RGDID:	1305646	Length:	464	Species:	Rattus norvegicus

Alignment Length:	388	Identity:	154/388 - (39%)
Similarity:	215/388 - (55%)	Gaps:	27/388 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKLLALLAVLCLSQV-IGAERIVNCYWGTWANYRSGNGKFDVSNIDAGLCTHLSYSFFGINDNG 64
            |.:.|||..|..|..: .|:...:.||:..||.||||..:|...::|..||||:.|:|.|:| |.
  Rat     1 MVQSLALAGVTTLLMIQWGSAAKLFCYFTNWAQYRSGAARFLPRDVDPNLCTHVIYAFAGLN-NH 64

  Fly    65 EIQSLDTWLDYDLGFINQAISLKNQNSNLKVLAVVGGWNEGSTKYSSMSGDWYKRQNFINSALNL 129
            ::.:::   ..|..|..:..|||.:|..||.|..||||:.|:.|::.|......||.|:||||:.
  Rat    65 QVSTVE---PNDELFYQELNSLKKRNPKLKTLLAVGGWSFGTQKFTDMVATASTRQTFVNSALSF 126

  Fly   130 LRNHGFDGLDLDWEYPNQRGGNWNDRANFVTLLREIKEAFAPYGYELG-------IAVGAGESLA 187
            ||.|||||||||||||..||....|:..|..|::::.:||.......|       .||..|....
  Rat   127 LRTHGFDGLDLDWEYPGSRGSPAVDKERFTALIQDLAKAFQEEARASGKSRLLLTAAVPTGRGHV 191

  Fly   188 SASYEIANIAQQVDFINVMTYDFAMASDGQTGFNAPQWA------------VENAINFWLSQGAP 240
            .|.||:..|.|.:||||:|.|||..:.|..||.|:|.:.            |:.|:..||.:|.|
  Rat   192 DAGYEVDKIVQSLDFINLMAYDFHSSWDKTTGHNSPLYKRQGETGKDAEKNVDAAVTLWLQKGTP 256

  Fly   241 ANKLVLGVGTYGRSFQLSDSSQNWPGAPCRGEGSAGSYTGSTGYLGYNEICQNNWHTVFDYDNAA 305
            |:||:||:..|||||.|:.||.:..|||..|.|:.|.||...|.|.|.|:|........: |...
  Rat   257 ASKLMLGMPAYGRSFTLASSSDSGVGAPATGPGAPGPYTKEKGILVYFEVCSWKGKQRIE-DQKV 320

  Fly   306 PYAYSGDQWVSFDNVLSVQYKMDFALSKGLAGAMIWSLETDDYRGQ-CGE-TYPLLKTINRKL 366
            ||...|:|||.||:..|.:.|..:...|||.|||:|.|:.||::|. |.| .|||::|::::|
  Rat   321 PYVSQGNQWVGFDDRESFRAKAAYVKQKGLGGAMVWILDGDDFKGSFCNEGQYPLIRTLHQEL 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht9	NP_611543.3	GH18_chitolectin_chitotriosidase	23..366	CDD:119351	146/363 (40%)
Cht9	NP_611543.3	Glyco_18	23..346	CDD:214753	137/341 (40%)
Chit1	NP_001073157.1	GH18_chitolectin_chitotriosidase	24..383	CDD:119351	146/363 (40%)
Chit1	NP_001073157.1	ChtBD2	416..463	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350388
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58170
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.860