DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht9 and lmd-5

DIOPT Version :9

Sequence 1:	NP_611543.3	Gene:	Cht9 / 37392	FlyBaseID:	FBgn0034582	Length:	368	Species:	Drosophila melanogaster
Sequence 2:	NP_001309512.1	Gene:	lmd-5 / 187942	WormBaseID:	WBGene00020141	Length:	1518	Species:	Caenorhabditis elegans

Alignment Length:	443	Identity:	118/443 - (26%)
Similarity:	193/443 - (43%)	Gaps:	122/443 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 AVLCLSQVIGAERIVNCYWGTWANYRSGNGKFDVSNIDAGLCTHLSYSFFGINDNGEIQ----SL 69
            |..|..:::|              |.:|.|:.:::.......||:.::|..:..:|.::    |.
Worm   985 AASCGKRIVG--------------YYTGWGEREITENQLKKLTHVIFAFVAMYADGSVKFGPVSA 1035

  Fly    70 DTWLDYDLG----------FINQAISLKNQNSNLKVLAVVGGWNEGSTKYSSMSGDWYKRQNFIN 124
            |     |.|          |::.....:..||.::||..|||| :.|..:||::.|..||:||::
Worm  1036 D-----DPGPQAGKKAERRFVDMKKKARAVNSGVRVLFAVGGW-DNSQYFSSVAADSGKRRNFVD 1094

  Fly   125 SALNLLRNHGFDGLDLDWEYPNQRGGNWNDRANFVTLLREIKEAFAPYG--------YELGIAVG 181
            |..:.:.:|..||:|||||||..:||   |:.|.|||:||::|.|....        |.:.:|..
Worm  1095 SVASFIEHHKIDGVDLDWEYPEMKGG---DKQNHVTLIRELRERFNGMASRNNRKDPYLITLASA 1156

  Fly   182 AGESLASASYEIANIAQQVDFINVMTYDFAMASDGQ----TGFNAPQW-----------AVENAI 231
            |||......|::..|....|||||||||:..|.:.:    ||..||.:           ..:.::
Worm  1157 AGEWNLREGYDLKGILNYADFINVMTYDYYGAWESKWGAYTGTPAPLYFGSLKGFSGKLNADFSM 1221

  Fly   232 NFWLSQGAPANKLVLGVGTYGRSF----QLSDSSQN-W-PGAPCRGEGSAGSYTGSTGYLGYNEI 290
            .|:.......::|.:||..|||.:    :..|:|.| | ..||     ..|.|.|  ||:|:..:
Worm  1222 KFYACNTKKPSQLTMGVPFYGRYWKNVLEPIDASDNMWRTAAP-----QNGKYEG--GYVGWRNL 1279

  Fly   291 CQNNWH---TVFDYDNAAPYAYSGD--QWVSFDNVLSVQYKMDFALSKGLAGAMIWSLETDD--- 347
            .:..|:   ..:......||..:..  .::.|:|..|::.|||:|.::.|.|.|||:|:.||
Worm  1280 EKEGWNKGSATWHKKTKTPYIMNNGARMFLGFENERSLKEKMDYATNRNLGGLMIWALDLDDDAD 1344

  Fly   348 ---------------------YR--------------------GQCGETYPLL 359
                                 |:                    ||||::.||:
Worm  1345 TLLNLVSSAGLCSGGSGDKITYKCVPIDDVRWWTPENSDENRQGQCGKSAPLI 1397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht9	NP_611543.3	GH18_chitolectin_chitotriosidase	23..366	CDD:119351	115/429 (27%)
Cht9	NP_611543.3	Glyco_18	23..346	CDD:214753	106/370 (29%)
lmd-5	NP_001309512.1	LysM	22..65	CDD:197609
		LysM	77..120	CDD:197609
		LysM	151..194	CDD:197609
		LysM	220..260	CDD:197609
		LysM	275..312	CDD:197609
		LysM	386..429	CDD:197609
		Self-incomp_S1	851..944	CDD:283566
		Glyco_18	991..1336	CDD:214753	105/374 (28%)
		GH18_chitinase-like	992..1336	CDD:299167	105/373 (28%)
		ChtBD1_GH18_2	1388..1435	CDD:211315	6/10 (60%)
		ChtBD1_GH18_2	1462..1513	CDD:211315
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164293
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4747
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740