DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht9 and Chia

DIOPT Version :9

Sequence 1:	NP_611543.3	Gene:	Cht9 / 37392	FlyBaseID:	FBgn0034582	Length:	368	Species:	Drosophila melanogaster
Sequence 2:	NP_997469.1	Gene:	Chia / 113901	RGDID:	1303058	Length:	473	Species:	Rattus norvegicus

Alignment Length:	392	Identity:	154/392 - (39%)
Similarity:	217/392 - (55%)	Gaps:	31/392 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKLLALLA-VLCLSQVIGAERIVNCYWGTWANYRSGNGKFDVSNIDAGLCTHLSYSFFGINDNG 64
            |.||:.:.. ||.|:..:|:...:.||:..||.||.|.|.|...:|:..|||||.|:|.|:.:|
  Rat     1 MAKLILVTGLVLLLNVQLGSAYNLVCYFTNWAQYRPGLGSFKPDDINPCLCTHLIYAFAGMQNN- 64

  Fly    65 EIQSLDTWLDYDLGFINQAIS-LKNQNSNLKVLAVVGGWNEGSTKYSSMSGDWYKRQNFINSALN 128
            :|.::: |.|..|   .:|.: |||:||.||.|..:||||.|:..:::|......||.||.|.:.
  Rat    65 QITTIE-WNDVTL---YKAFNDLKNRNSKLKTLLAIGGWNFGTAPFTTMVSTSQNRQTFITSVIK 125

  Fly   129 LLRNHGFDGLDLDWEYPNQRGGNWNDRANFVTLLREIKEAFAPYGYE-------LGIAVGAGESL 186
            .||.:||||||||||||..||....|:..|..|::|::|||.....|       :..||.||.|.
  Rat   126 FLRQYGFDGLDLDWEYPGSRGSPPQDKHLFTVLVKELREAFEQEAIESNRPRLMVTAAVAAGISN 190

  Fly   187 ASASYEIANIAQQVDFINVMTYDFAMASDGQTGFNAPQWA------------VENAINFWLSQGA 239
            ..|.|||..::|.:|||:|||||...:.||.||.|:|.:.            |:..:|:|...||
  Rat   191 IQAGYEIPELSQYLDFIHVMTYDLHGSWDGYTGENSPLYKLPTETGSNAYLNVDYVMNYWKDNGA 255

  Fly   240 PANKLVLGVGTYGRSFQLSDSSQNWPGAPCRGEGSAGSYTGSTGYLGYNEIC---QNNWHTVFDY 301
            ||.||::|...||.::.||:.|....|||..|.|.||.||...|:..|.|||   :|.....:|.
  Rat   256 PAEKLIVGFPEYGHTYILSNPSDTGIGAPTSGNGPAGPYTRQAGFWAYYEICTFLRNGATQDWDA 320

  Fly   302 DNAAPYAYSGDQWVSFDNVLSVQYKMDFALSKGLAGAMIWSLETDDYRGQ-CGE-TYPLLKTINR 364
            ....||||.|::||.:||:.|...|..:.......|||||:::.||:.|. |.: .:||..|:|:
  Rat   321 PQEVPYAYKGNEWVGYDNIKSFSVKAQWLKQNNFGGAMIWAIDLDDFTGSFCDQGKFPLTSTLNK 385

  Fly   365 KL 366
            .|
  Rat   386 AL 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht9	NP_611543.3	GH18_chitolectin_chitotriosidase	23..366	CDD:119351	146/367 (40%)
Cht9	NP_611543.3	Glyco_18	23..346	CDD:214753	138/345 (40%)
Chia	NP_997469.1	GH18_chitolectin_chitotriosidase	24..387	CDD:119351	146/367 (40%)
		Glyco_18	24..365	CDD:214753	138/345 (40%)
		Chitooligosaccharide binding. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01258	70..71		0/1 (0%)
		Chitooligosaccharide binding. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01258	97..100		2/2 (100%)
		Chitooligosaccharide binding. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01258	210..213		2/2 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	395..421
		ChtBD2	426..473	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58170
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.030