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Protein Alignment Cht9 and CHI3L2

DIOPT Version :9

Sequence 1:	NP_611543.3	Gene:	Cht9 / 37392	FlyBaseID:	FBgn0034582	Length:	368	Species:	Drosophila melanogaster
Sequence 2:	NP_003991.2	Gene:	CHI3L2 / 1117	HGNCID:	1933	Length:	390	Species:	Homo sapiens

Alignment Length:	395	Identity:	145/395 - (36%)
Similarity:	209/395 - (52%)	Gaps:	50/395 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LLALLAVLCLSQVIGAERIVNCYWGTWANYRSGNGKFDVSNIDAGLCTHLSYSFFGINDN----- 63
            |.|.:.||.|.|...|.::| ||:..|:..|...|||...|||..||:||.|||..|.:|
Human    11 LWAGVVVLLLLQGGSAYKLV-CYFTNWSQDRQEPGKFTPENIDPFLCSHLIYSFASIENNKVIIK 74

  Fly    64 --GEIQSLDTWLDYDLGFINQAISLKNQNSNLKVLAVVGGWNEGSTKYSSMSGDWYKRQNFINSA 126
              .|:....|        ||   |||.:|..||:|..:||:..||..:..|......|..||||.
Human    75 DKSEVMLYQT--------IN---SLKTKNPKLKILLSIGGYLFGSKGFHPMVDSSTSRLEFINSI 128

  Fly   127 LNLLRNHGFDGLDLDWEYPNQRGGNWNDRANFVTLLREIKEAF-------APYGYELGIAVGAGE 184
            :..||||.|||||:.|.||:|:     :..:|..|:.|:.|||       ......|...|.||.
Human   129 ILFLRNHNFDGLDVSWIYPDQK-----ENTHFTVLIHELAEAFQKDFTKSTKERLLLTAGVSAGR 188

  Fly   185 SLASASYEIANIAQQVDFINVMTYDFAMASDGQ--TGFNAP------------QWAVENAINFWL 235
            .:...||::..:|:.:||||::::||..:.:..  ||.|:|            .:.||.|:.:|:
Human   189 QMIDNSYQVEKLAKDLDFINLLSFDFHGSWEKPLITGHNSPLSKGWQDRGPSSYYNVEYAVGYWI 253

  Fly   236 SQGAPANKLVLGVGTYGRSFQLSDSSQNWPGAPCRGEGSAGSYTGSTGYLGYNEICQ--NNWHTV 298
            .:|.|:.|:|:|:.|||.||.|: |::...|||..|.|:||..|.|:|:|.|.||||  ......
Human   254 HKGMPSEKVVMGIPTYGHSFTLA-SAETTVGAPASGPGAAGPITESSGFLAYYEICQFLKGAKIT 317

  Fly   299 FDYDNAAPYAYSGDQWVSFDNVLSVQYKMDFALSKGLAGAMIWSLETDDYRGQ-CGE-TYPLLKT 361
            ...|...|||..|:|||.:|:|.|::.|:.|..:..|.||||||::.||:.|: |.: .|||::.
Human   318 RLQDQQVPYAVKGNQWVGYDDVKSMETKVQFLKNLNLGGAMIWSIDMDDFTGKSCNQGPYPLVQA 382

  Fly   362 INRKL 366
            :.|.|
Human   383 VKRSL 387

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.