DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht9 and chia.5

DIOPT Version :9

Sequence 1:	NP_611543.3	Gene:	Cht9 / 37392	FlyBaseID:	FBgn0034582	Length:	368	Species:	Drosophila melanogaster
Sequence 2:	NP_001103511.2	Gene:	chia.5 / 100003900	ZFINID:	ZDB-GENE-071004-113	Length:	481	Species:	Danio rerio

Alignment Length:	379	Identity:	158/379 - (41%)
Similarity:	207/379 - (54%)	Gaps:	36/379 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LALLAVLCLSQVIGAERIVNCYWGTWANYRSGNGKFDVSNIDAGLCTHLSYSFFGINDNGEIQSL 69
            |||......||:|       ||:..|:.||...||:..||:|..|||||.|:|..||:..::.:.
Zfish    12 LALCHFGLASQLI-------CYFTNWSQYRPDVGKYMPSNVDPHLCTHLIYAFSIINNENKLTTY 69

  Fly    70 DTWLDYDLGFINQAIS-LKNQNSNLKVLAVVGGWNEGSTKYSSMSGDWYKRQNFINSALNLLRNH 133
            : |.|..|   .|:.: ||..|||||.|..||||..||.::|||......||.||.|::..||.|
Zfish    70 E-WNDETL---YQSFNGLKQSNSNLKTLLAVGGWEFGSAQFSSMVSMPQNRQTFIQSSITFLRTH 130

  Fly   134 GFDGLDLDWEYPNQRGGNWNDRANFVTLLREIKEAFAPYGYELG-------IAVGAGESLASASY 191
            ||||||||||||..||....|:..|..|.:|:.||:.......|       .||.|.:.:..|.|
Zfish   131 GFDGLDLDWEYPGSRGSPPEDKQRFTLLCKELVEAYQAESAATGRPRLMLTAAVAAVKGIIDAGY 195

  Fly   192 EIANIAQQVDFINVMTYDFAMASDGQTGFNAP------------QWAVENAINFWLSQGAPANKL 244
            |||.||:.:||||:|||||..:.|..||.|:|            .:..:.|:|:|..||||..||
Zfish   196 EIAEIAKYLDFINIMTYDFHGSQDNITGHNSPLYRDSGDTGDQIYYNTDFAMNYWRDQGAPVEKL 260

  Fly   245 VLGVGTYGRSFQLSDSSQNWPGAPCRGEGSAGSYTGSTGYLGYNEICQNNWHTVFD--YDNAAPY 307
            .:|...|||:|:|| |:.|..|||..|...||:||...|:..|.|||......:..  .|...||
Zfish   261 RMGFAAYGRTFRLS-SADNGVGAPASGAALAGTYTREAGFWSYYEICTFLQGAIVQQIVDQKVPY 324

  Fly   308 AYSGDQWVSFDNVLSVQYKMDFALSKGLAGAMIWSLETDDYRGQ-CGE-TYPLL 359
            |..|.:||.||:..|.:.|:|:...||..||.:|||:.||:.|| ||: .|||:
Zfish   325 ATKGQEWVGFDDQESYETKVDYLKEKGFGGAFVWSLDLDDFSGQFCGQGKYPLI 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht9	NP_611543.3	GH18_chitolectin_chitotriosidase	23..366	CDD:119351	152/361 (42%)
Cht9	NP_611543.3	Glyco_18	23..346	CDD:214753	143/344 (42%)
chia.5	NP_001103511.2	Glyco_18	22..363	CDD:214753	145/352 (41%)
		GH18_chitolectin_chitotriosidase	23..381	CDD:119351	153/368 (42%)
		CBM_14	433..479	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910