DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cht8 and chia

DIOPT Version :9

Sequence 1:	NP_611542.2	Gene:	Cht8 / 37390	FlyBaseID:	FBgn0034580	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_001186489.1	Gene:	chia / 548404	XenbaseID:	XB-GENE-5868468	Length:	482	Species:	Xenopus tropicalis

Alignment Length:	498	Identity:	187/498 - (37%)
Similarity:	272/498 - (54%)	Gaps:	51/498 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LVKLLLGVILMAASSSAQGNSSKNVVCYQGTWSVYRPGLGKFGMEDIDPFLCTHLIYAFLGIEET 71
            :.||:| ::.:|...:||..|:..:.||...|:.||||||||..::|||.|||||||||.|: ..
Frog     1 MAKLIL-LVGLALVLNAQLGSAYELTCYFTNWAQYRPGLGKFKPDNIDPCLCTHLIYAFAGM-SN 63

  Fly    72 GQLRVIDAYLDLEENSGRGNIKSFNALKLKNPVLKTLVAVGGWNEGSKRFSLVARDPSKREKFVD 136
            .|:..|: :.|:...|      ||..||.:|..||||:|:||||.|:..|:.:......|:.|:.
Frog    64 NQITTIE-WNDVTLYS------SFQNLKNQNGNLKTLLAIGGWNFGTAPFTAMVATAQSRQTFIS 121

  Fly   137 DVVRFLQRHGFDGLDLDWEYPGQRHSLDNEDRSNYITFLKELKEGLEPFG-------FILSAAVG 194
            .|::||:::||||||.||||||.|.| ..:|:..:.|.::|:....|...       .:::|||.
Frog   122 SVIKFLRQYGFDGLDFDWEYPGSRGS-PPQDKQLFTTLVQEMLAAFEAEASQSNKPRLMVTAAVA 185

  Fly   195 SAQFSAEISYDIPAMVPYLDLINVMAYDLHGPWDQVVGINAPLYAAEKDASDSSGRQQQLNVDAV 259
            :...:.|..|.||.:...||.|:||.|||||.|:...|.|:|||.    ...::|....||||.|
Frog   186 AGISNIESGYQIPQLSQALDYIHVMTYDLHGSWEGYTGENSPLYT----NPSATGYNAYLNVDYV 246

  Fly   260 VKYWLKAGAPAEKLILGVPFYGRSFTLATAEGNQPGAPHIGKGIAGNYSREPGVLGYNELCEMME 324
            :.|||..||||.|||:|.|.||.:|.|:....|..|||..|.|.||.|:|:.|...|.|:|..::
Frog   247 MNYWLNNGAPASKLIVGFPTYGHTFILSNPSNNGIGAPTSGNGPAGPYTRQAGFWAYYEICTFLK 311

  Fly   325 REEWTQKWEATQQVPYAYRQRQWVGYEDPRSLALKAQYVMDNHLGGIMIWSLESDDFRGT-CGQQ 388
            ... |..|.:.:.|||||:..:|:||::.:|..:||:::|.|:|||.|:|:::.|||.|| |.|.
Frog   312 NGA-TNLWSSAEDVPYAYQGSEWLGYDNEKSFQIKAEWLMKNNLGGAMVWAIDLDDFTGTFCNQG 375

  Fly   389 PYPLLHEINRVL---FGGNTP-----------------------SGLTTESNRESPSEGFSCPAD 427
            .:||::.:...|   ..|.||                       ||..:.|...|...|| |...
Frog   376 KFPLINTLKNTLGVQASGCTPPATPVAPVTAAPATVPSGSGSGSSGSGSSSGGSSGGSGF-CAGK 439

  Fly   428 APAGYIRDPDNCSKFYYCSGGKTHNFDCPSGLNFDLDTKSCNY 470
            | :|......|.:.|::|..|.|:...|.:||.||...:.||:
Frog   440 A-SGLYPVAGNTNAFWHCLNGITYQQHCQTGLVFDPSCECCNW 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht8	NP_611542.2	GH18_chitolectin_chitotriosidase	31..400	CDD:119351	155/376 (41%)
		Glyco_18	31..379	CDD:214753	146/354 (41%)
		CBM_14	424..476	CDD:279884	15/47 (32%)
chia	NP_001186489.1	GH18_chitolectin_chitotriosidase	24..387	CDD:119351	155/376 (41%)
		Glyco_18	26..365	CDD:214753	146/352 (41%)
		CBM_14	436..482	CDD:279884	15/47 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2066
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.040