back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cht8 and OVGP1

DIOPT Version :9

Sequence 1:	NP_611542.2	Gene:	Cht8 / 37390	FlyBaseID:	FBgn0034580	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_002548.3	Gene:	OVGP1 / 5016	HGNCID:	8524	Length:	678	Species:	Homo sapiens

Alignment Length:	411	Identity:	160/411 - (38%)
Similarity:	228/411 - (55%)	Gaps:	40/411 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MWSVSGLVKLLLGVILMAASSSAQGNSSKNVVCYQGTWSVYRPGLGKFGMEDIDPFLCTHLIYAF 65
            ||      ||||.|.|:.......|.:.| :|||...|:..|||.......|:|||||||||:||
Human     1 MW------KLLLWVGLVLVLKHHDGAAHK-LVCYFTNWAHSRPGPASILPHDLDPFLCTHLIFAF 58

  Fly    66 LGIEETGQLRVIDAYLDLEENSGRGNIKSFNALKLKNPVLKTLVAVGGWNEGSKRFSLVARDPSK 130
            ..:...   :::..  ||::.  :.....||.||.:|..||||:::||||.|:.||:.:....:.
Human    59 ASMNNN---QIVAK--DLQDE--KILYPEFNKLKERNRELKTLLSIGGWNFGTSRFTTMLSTFAN 116

  Fly   131 REKFVDDVVRFLQRHGFDGLDLDWEYPGQRHSLDNEDRSNYITFLKEL-----KEGL---EPFGF 187
            ||||:..|:..|:.|.||||||.:.|||.|.| ...||..::..::||     ||.|   .| ..
Human   117 REKFIASVISLLRTHDFDGLDLFFLYPGLRGS-PMHDRWTFLFLIEELLFAFRKEALLTMRP-RL 179

  Fly   188 ILSAAVGSAQFSAEISYDIPAMVPYLDLINVMAYDLHGPWDQVVGINAPLYAAEKDASDSSGRQQ 252
            :|||||.......:.|||:..:...||.|||::|||||.|::..|.|:||::..:|...|:
Human   180 LLSAAVSGVPHIVQTSYDVRFLGRLLDFINVLSYDLHGSWERFTGHNSPLFSLPEDPKSSA---- 240

  Fly   253 QLNVDAVVKYWLKAGAPAEKLILGVPFYGRSFTLATAEGNQPGAPHIGKGIAGNYSREPGVLGYN 317
                 ..:.||.|.|||:||||:|:|.|||:|.|..|..|...|..||....|.|:::.|.|.|.
Human   241 -----YAMNYWRKLGAPSEKLIMGIPTYGRTFRLLKASKNGLQARAIGPASPGKYTKQEGFLAYF 300

  Fly   318 ELCEMMEREEWTQK--WEATQQVPYAYRQRQWVGYEDPRSLALKAQYVMDNHLGGIMIWSLESDD 380
            |:|..:    |..|  |...|.||||.:.::||||::..|.:.||.::...|.||.|:|:|:.||
Human   301 EICSFV----WGAKKHWIDYQYVPYANKGKEWVGYDNAISFSYKAWFIRREHFGGAMVWTLDMDD 361

  Fly   381 FRGT-CGQQPYPLLHEINRVL 400
            .||| ||..|:||::.:|.:|
Human   362 VRGTFCGTGPFPLVYVLNDIL 382

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.