DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht8 and Cht4

DIOPT Version :9

Sequence 1:	NP_611542.2	Gene:	Cht8 / 37390	FlyBaseID:	FBgn0034580	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_524962.2	Gene:	Cht4 / 49815	FlyBaseID:	FBgn0022700	Length:	462	Species:	Drosophila melanogaster

Alignment Length:	492	Identity:	209/492 - (42%)
Similarity:	288/492 - (58%)	Gaps:	58/492 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MWSVSGLVKLLLGVILMAASSSAQGNSSKNVVCYQGTWSVYRPGLGKFGMEDIDPFLCTHLIYAF 65
            :|:::.|. |.||.:         .:|.|.:.||.|||:.||||.|||...||||.||||:.|.|
  Fly     6 IWALAALC-LCLGQV---------ASSEKLLNCYWGTWANYRPGDGKFTPSDIDPSLCTHISYTF 60

  Fly    66 LGIEETGQLRVIDAYLDLEENSGRGNIKSFNALKLKNPVLKTLVAVGGWNEGSKRFSLVARDPSK 130
            .||.:.|:.:.:|.:||:::  |.|.|....|||.:||.||.|..||||||||.::|.:|.||:|
  Fly    61 FGISDAGEFKSLDTWLDMDD--GLGFISQTIALKQRNPNLKILAVVGGWNEGSTKYSAMAADPAK 123

  Fly   131 REKFVDDVVRFLQRHGFDGLDLDWEYPGQRHSLDNEDRSNYITFLKELKEGLEPFGFILSAAVGS 195
            |..||...:.|:|::.||||||||||||||.. ...||.|::|.|:|:||..:.:|..|..|||:
  Fly   124 RATFVSTSLAFIQQYSFDGLDLDWEYPGQRGG-SEADRENFVTLLREIKETYDQYGLELGIAVGA 187

  Fly   196 AQFSAEISYDIPAMVPYLDLINVMAYDLHGPWDQVVGINAPLYAAEKDASDSSGRQQQLNVDAVV 260
            ::.||.|||||||:..:|..||||.||.|...|..:|:||||    .:.::|            :
  Fly   188 SEKSASISYDIPAISQHLTFINVMTYDFHMALDGYLGLNAPL----PEVAES------------I 236

  Fly   261 KYWLKAGAPAEKLILGVPFYGRSFTLATAEGNQPGAPHIGKGIAGNYSREPGVLGYNELCEMMER 325
            .|||..||||||||||:.|||.|:.::.:..|.|||..||.|.||.|:||.|.|||:|:|    .
  Fly   237 DYWLSHGAPAEKLILGIGFYGHSYQMSDSSQNWPGAACIGPGTAGVYTRENGFLGYHEIC----L 297

  Fly   326 EEWTQKWEATQQVPYAYRQRQWVGYEDPRSLALKAQYVMDNHLGGIMIWSLESDDFRGTCGQQPY 390
            ..|...::.....|||::..||:||::|.|:.||.|.|...:|||.|:||:|:|||||.||:. |
  Fly   298 NNWQTVFDQENGAPYAFQGDQWIGYDNPESIQLKMQLVESRNLGGAMMWSIETDDFRGLCGES-Y 361

  Fly   391 PLLHEINRVL----------FGGNTPSGLTTESNRESPSEGFSCPADAPAG------------YI 433
            |||..:||.|          .||....|..|.:...:|:.. ..||..|.|            ::
  Fly   362 PLLKTMNRALGREVSGGSGGGGGGGGEGSVTPAPTAAPTSS-PTPAPTPGGGSGGNECAQDGFFV 425

  Fly   434 RDPDNCSKFYYCSGGKTHNFDCPSGLNFDLDTKSCNY 470
            .:.| |:|||.|.||..::|.|.:||.|:..|.:|::
  Fly   426 LESD-CNKFYQCVGGVRYDFQCGAGLCFNTITLNCDW 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht8	NP_611542.2	GH18_chitolectin_chitotriosidase	31..400	CDD:119351	177/368 (48%)
		Glyco_18	31..379	CDD:214753	164/347 (47%)
		CBM_14	424..476	CDD:279884	19/59 (32%)
Cht4	NP_524962.2	GH18_chitolectin_chitotriosidase	26..371	CDD:119351	177/368 (48%)
		Glyco_18	28..351	CDD:214753	164/345 (48%)
		CBM_14	421..462	CDD:279884	15/42 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469217
Domainoid	1	1.000	188	1.000	Domainoid score	I962
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I1632
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	1	1.000	-	-		mtm1002
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
	10	9.900