DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht8 and Cht9

DIOPT Version :9

Sequence 1:	NP_611542.2	Gene:	Cht8 / 37390	FlyBaseID:	FBgn0034580	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_611543.3	Gene:	Cht9 / 37392	FlyBaseID:	FBgn0034582	Length:	368	Species:	Drosophila melanogaster

Alignment Length:	395	Identity:	168/395 - (42%)
Similarity:	230/395 - (58%)	Gaps:	30/395 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 GLVKLLLGVILMAASSSAQGNSSKNVVCYQGTWSVYRPGLGKFGMEDIDPFLCTHLIYAFLGIEE 70
            |.:..||.|:.::....|:    :.|.||.|||:.||.|.|||.:.:||..|||||.|:|.||.:
  Fly     2 GKLLALLAVLCLSQVIGAE----RIVNCYWGTWANYRSGNGKFDVSNIDAGLCTHLSYSFFGIND 62

  Fly    71 TGQLRVIDAYLDLEENSGRGNIKSFNALKLKNPVLKTLVAVGGWNEGSKRFSLVARDPSKREKFV 135
            .|:::.:|.:||.:    .|.|....:||.:|..||.|..||||||||.::|.::.|..||:.|:
  Fly    63 NGEIQSLDTWLDYD----LGFINQAISLKNQNSNLKVLAVVGGWNEGSTKYSSMSGDWYKRQNFI 123

  Fly   136 DDVVRFLQRHGFDGLDLDWEYPGQRHSLDNEDRSNYITFLKELKEGLEPFGFILSAAVGSAQFSA 200
            :..:..|:.|||||||||||||.||....| ||:|::|.|:|:||...|:|:.|..|||:.:..|
  Fly   124 NSALNLLRNHGFDGLDLDWEYPNQRGGNWN-DRANFVTLLREIKEAFAPYGYELGIAVGAGESLA 187

  Fly   201 EISYDIPAMVPYLDLINVMAYDLHGPWDQVVGINAPLYAAEKDASDSSGRQQQLNVDAVVKYWLK 265
            ..||:|..:...:|.||||.||.....|...|.|||.:|.|.                .:.:||.
  Fly   188 SASYEIANIAQQVDFINVMTYDFAMASDGQTGFNAPQWAVEN----------------AINFWLS 236

  Fly   266 AGAPAEKLILGVPFYGRSFTLATAEGNQPGAPHIGKGIAGNYSREPGVLGYNELCEMMEREEWTQ 330
            .||||.||:|||..|||||.|:.:..|.||||..|:|.||:|:...|.|||||:|:    ..|..
  Fly   237 QGAPANKLVLGVGTYGRSFQLSDSSQNWPGAPCRGEGSAGSYTGSTGYLGYNEICQ----NNWHT 297

  Fly   331 KWEATQQVPYAYRQRQWVGYEDPRSLALKAQYVMDNHLGGIMIWSLESDDFRGTCGQQPYPLLHE 395
            .::.....||||...|||.:::..|:..|..:.:...|.|.||||||:||:||.|| :.||||..
  Fly   298 VFDYDNAAPYAYSGDQWVSFDNVLSVQYKMDFALSKGLAGAMIWSLETDDYRGQCG-ETYPLLKT 361

  Fly   396 INRVL 400
            |||.|
  Fly   362 INRKL 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht8	NP_611542.2	GH18_chitolectin_chitotriosidase	31..400	CDD:119351	162/368 (44%)
		Glyco_18	31..379	CDD:214753	149/347 (43%)
		CBM_14	424..476	CDD:279884
Cht9	NP_611543.3	GH18_chitolectin_chitotriosidase	23..366	CDD:119351	162/368 (44%)
Cht9	NP_611543.3	Glyco_18	23..346	CDD:214753	149/347 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469218
Domainoid	1	1.000	188	1.000	Domainoid score	I962
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I1632
Isobase	1	0.950	-	0	Normalized mean entropy	S2811
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	1	1.000	-	-		mtm1002
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
	11	10.850