DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht8 and Idgf5

DIOPT Version :9

Sequence 1:	NP_611542.2	Gene:	Cht8 / 37390	FlyBaseID:	FBgn0034580	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_611321.3	Gene:	Idgf5 / 37104	FlyBaseID:	FBgn0064237	Length:	444	Species:	Drosophila melanogaster

Alignment Length:	451	Identity:	124/451 - (27%)
Similarity:	206/451 - (45%)	Gaps:	86/451 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LGVILMAASSSAQGNSSK--NVVCYQGTWSVYRPGLGKFGMEDIDPFL--CTHLIYAFLGIEE-T 71
            ||::|.:..:..|...::  .:||:....|..|.|..:..:.:::|.|  |..|:|.:.||:. |
  Fly    10 LGLLLCSFLAFFQSTYAEVGKLVCFYDAQSFVREGPAQMSLAELEPALQFCNFLVYGYAGIDAVT 74

  Fly    72 GQLRVIDAYLDLEENSGRGNIKSFNALKLKNPVLKTLVAVGG----WNEG---SKRFSLVARDPS 129
            .:::.:|..|    .:.|.:.:...||:.|.|.::.|::|||    .:||   |.::..:.....
  Fly    75 YKIKSLDPSL----TNDRQHYRHITALRKKYPHVRFLLSVGGDRDVNSEGVADSDKYLRLLEQSE 135

  Fly   130 KREKFVDDVVRFLQRHGFDGLDLDWEYPGQRHSL------------------------DNEDRSN 170
            .|:.|...|:..|..:||||:||.|::|..|..|                        ..|.|..
  Fly   136 HRKSFQASVLAELNNNGFDGIDLAWQFPKNRPKLQQGVFKRVWGSLRGWFSSSSVDEKSEEHREQ 200

  Fly   171 YITFLKELKEGLEPFGFILSAAVGSAQFSAEISYDIPAMVPYLDLINVMAYDLHGPW--DQVVGI 233
            :.|.|:||:..|...|.:|:.:: ....|||:..|:|.::..:|.:|:..||...|.  .:|..:
  Fly   201 FATLLEELQSDLRRGGQLLTVSM-LPHVSAELFIDVPKVLSNVDFVNLGTYDFQTPERDPKVADL 264

  Fly   234 NAPLYAA-EKDASDSSGRQQQLNVDAVVKYWLK--AGAPAEKLILGVPFYGRSFTLATAEGNQPG 295
            ..||||. ::|.|.        ||...|:||:.  :.....||.:||..|||::.: |......|
  Fly   265 PTPLYAMYDRDPSH--------NVQYQVQYWMNQTSEISVHKLHVGVTSYGRAWNM-TRNSGITG 320

  Fly   296 APHI----GKGIAGNYSREPGVLGYNELCEMMEREEWTQKWEATQQVP--------------YAY 342
            .|.|    |....|..:..||:|.:.|:|::::::      ...::||              |||
  Fly   321 YPPIPAANGAAPPGRQTVTPGLLSWPEICDLLQQQ------PQDREVPHLRKVGDPTKRFGIYAY 379

  Fly   343 RQRQ-------WVGYEDPRSLALKAQYVMDNHLGGIMIWSLESDDFRGTCGQQPYPLLHEI 396
            |...       |||||||.:.|:||.:|....|||:....|..|||||.|..:.:|:|..|
  Fly   380 RAADDQGENGLWVGYEDPLTAAIKAGFVHAQGLGGVAFHDLSMDDFRGQCAGEKFPILRSI 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht8	NP_611542.2	GH18_chitolectin_chitotriosidase	31..400	CDD:119351	120/430 (28%)
		Glyco_18	31..379	CDD:214753	111/411 (27%)
		CBM_14	424..476	CDD:279884
Idgf5	NP_611321.3	GH18_IDGF	30..444	CDD:119352	120/431 (28%)
Idgf5	NP_611321.3	Glyco_18	30..423	CDD:214753	111/412 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463815
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840