DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht8 and Idgf6

DIOPT Version :9

Sequence 1:	NP_611542.2	Gene:	Cht8 / 37390	FlyBaseID:	FBgn0034580	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_001286499.1	Gene:	Idgf6 / 36868	FlyBaseID:	FBgn0013763	Length:	452	Species:	Drosophila melanogaster

Alignment Length:	456	Identity:	136/456 - (29%)
Similarity:	213/456 - (46%)	Gaps:	77/456 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LVKLLLGVILMAASSSAQGNSS-----KNVVCYQGTWSVYRPGLGKFGMEDIDPFL--CTHLIYA 64
            ::|.|..|.|..||..|....:     |::|||..:.|..:.||||..:::::|.|  |.:|:|.
  Fly     2 IIKALAIVSLCLASIQASKVGAPQLPKKHLVCYYDSASFVKEGLGKLVIDELEPALQFCDYLVYG 66

  Fly    65 FLGIEETGQLRV-IDAYLDLEENSGRGNIKSFNALKLKNPVLKTLVAVGG---------WNEGSK 119
            :.|||......| ::..|||:  .|:|..::...||.|.|.:|.|::|||         ..|...
  Fly    67 YAGIERDSHKAVSLNQQLDLD--LGKGLYRTVTRLKRKYPNVKILLSVGGDKDIELDKDAKELPN 129

  Fly   120 RFSLVARDPSKREKFVDDVVRFLQRHGFDGLDLDWEYPGQR----HS------------------ 162
            ::..:...|:.|.:||:.|...::.:||||||:.|::|..:    ||
  Fly   130 KYLELLESPTGRTRFVNTVYSLVKTYGFDGLDVAWQFPKNKPKKVHSGIGSLWKGFKKVFSGDSI 194

  Fly   163 ---LDNEDRSNYITFLKELKEGLEPFGFILSAAVGSAQFSAEISYDIPAMVPYLDLINVMAYDLH 224
               ...|.:..:...|:::|....|...:||..| ....::.:.|||||:|.|||.:|:..:|..
  Fly   195 VDEKSEEHKEQFTALLRDVKNAFRPDNLLLSTTV-LPNVNSSLFYDIPAVVNYLDFVNLGTFDFF 258

  Fly   225 GPW--DQVVGINAPLYAAEKDASDSSGRQQQLNVDAVVKYWLKAGAPAEKLILGVPFYGRSFTLA 287
            .|.  .:|....||:|       :.|.|..:.||.|.|||||:...||.|:.:||..|||.:.|
  Fly   259 TPQRNPEVADYAAPIY-------ELSERNPEFNVAAQVKYWLRNNCPASKINVGVATYGRPWKL- 315

  Fly   288 TAEGNQPGAPHI----GKGIAGNYSREPGVLGYNELCEMMEREEWTQKWEATQ-----QVP---- 339
            |.:....|.|.:    .:...|..::.||:..:.|:|.::..:.......|..     |.|
  Fly   316 TDDSGDTGVPPVKDVKDEAPVGGNTQVPGIYSWPEVCALLPNQNNAYLKGANAPLIKVQDPAKRF 380

  Fly   340 --YAYRQRQ-------WVGYEDPRSLALKAQYVMDNHLGGIMIWSLESDDFRGTCGQQPYPLLHE 395
              ||||...       ||.:|||.:.|.||.||...:|||:.::.|..|||||.|..:.||:|..
  Fly   381 GSYAYRAADKKGDNGIWVSFEDPDTAADKAGYVRTENLGGVALFDLSYDDFRGLCTNEKYPILRA 445

  Fly   396 I 396
            |
  Fly   446 I 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht8	NP_611542.2	GH18_chitolectin_chitotriosidase	31..400	CDD:119351	128/427 (30%)
		Glyco_18	31..379	CDD:214753	118/408 (29%)
		CBM_14	424..476	CDD:279884
Idgf6	NP_001286499.1	GH18_IDGF	30..450	CDD:119352	128/428 (30%)
Idgf6	NP_001286499.1	Glyco_18	31..429	CDD:214753	118/408 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463811
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	115	1.000	Inparanoid score	I1336
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
	6	5.890