DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cht8 and Idgf3

DIOPT Version :9

Sequence 1:	NP_611542.2	Gene:	Cht8 / 37390	FlyBaseID:	FBgn0034580	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_001285982.1	Gene:	Idgf3 / 34981	FlyBaseID:	FBgn0020414	Length:	441	Species:	Drosophila melanogaster

Alignment Length:	453	Identity:	118/453 - (26%)
Similarity:	209/453 - (46%)	Gaps:	77/453 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VSGLVKLLLGVILMAASSSAQGNSSKNVVCYQGTWSVYRPGLGKFGMEDIDPFL--CTHLIYAFL 66
            ::|.:.|.|.:.| |..:..:.:::.|:||:..:....|.||.:|.|.||:..|  ||||:|.:.
  Fly     1 MTGSLWLSLALSL-AVLAQFKVSAAPNLVCFYDSQGSQRQGLAQFSMIDIELALQFCTHLVYGYA 64

  Fly    67 GIE-ETGQLRVIDAYLDLEENSGRGNIKSFNALKLKNPVLKTLVAVGG---WNEGSKRFSLVARD 127
            |:. :..:::.|:..||||:.    ::....::|.:.|.:|.|::|||   ..||::...|:...
  Fly    65 GVNADNYEMQSINKRLDLEQR----HLAQITSMKERYPHIKFLLSVGGDADTYEGNQYIKLLESG 125

  Fly   128 PSKREKFVDDVVRFLQRHGFDGLDLDWEYPGQR----H--------------------SLDNEDR 168
            .....:|::.....::|:.||||||..:.|..:    |                    ..::|..
  Fly   126 QQGHRRFIESARDLVRRYNFDGLDLALQLPRNKPRKVHGDVGSAWKSFKKFFTGDFIVDTESETH 190

  Fly   169 SNYIT-FLKELKEGLEPFGFILSAAVGSAQFSAEISYDIPAMVPYLDLINVMAYDLHGPW--DQV 230
            ...:| .:|:|...|:....:||..| ....::...||.|::.|.||.||:..:|...|.  .:.
  Fly   191 KGQVTALIKDLSAALKQNDLLLSLTV-LPNVNSSWYYDAPSIAPSLDFINLGTFDFLTPQRNPEE 254

  Fly   231 VGINAPLYAAEKDASDSSGRQQQLNVDAVVKYWLKAGAPAEKLILGVPFYGRSFTLATAEGNQPG 295
            ...:||.|.|.     ...|....|::..:::||....||.|:.:|:..||||:.::...|:. |
  Fly   255 ADFSAPTYEAV-----GQNRLGHYNLNFQMEHWLLQRVPANKINIGIATYGRSWKMSKDSGDS-G 313

  Fly   296 APHI----GKGIAGNYSREPGVLGYNELCEMMERE----------------EWTQKWEATQQVPY 340
            .|.:    |...||..|::.|:|.:.|:|.:|...                :.|:::.:     |
  Fly   314 MPVVPSTQGPAPAGPQSKQEGLLNWAEICSLMPNPSNSNARGPNAPVKRVVDPTKRYGS-----Y 373

  Fly   341 AYRQRQ-------WVGYEDPRSLALKAQYVMDNHLGGIMIWSLESDDFRGTCGQQPYPLLHEI 396
            |:|...       |:.|:||.|.:.||.|....:|||:.::.|..|||||.|....:|:|..|
  Fly   374 AFRAADENGDHGLWISYDDPDSASSKAMYARARNLGGVALFDLTQDDFRGQCTNDRFPMLRAI 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht8	NP_611542.2	GH18_chitolectin_chitotriosidase	31..400	CDD:119351	112/426 (26%)
		Glyco_18	31..379	CDD:214753	103/407 (25%)
		CBM_14	424..476	CDD:279884
Idgf3	NP_001285982.1	GH18_IDGF	26..440	CDD:119352	113/427 (26%)
Idgf3	NP_001285982.1	Glyco_18	27..419	CDD:214753	103/407 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463814
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840