DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht8 and Idgf1

DIOPT Version :9

Sequence 1:	NP_611542.2	Gene:	Cht8 / 37390	FlyBaseID:	FBgn0034580	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_477258.1	Gene:	Idgf1 / 34978	FlyBaseID:	FBgn0020416	Length:	439	Species:	Drosophila melanogaster

Alignment Length:	454	Identity:	128/454 - (28%)
Similarity:	204/454 - (44%)	Gaps:	85/454 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VKLLLGVILMAASSSAQGNSSKNVVCYQGTWSVYRPGLGKFGMEDIDPFL--CTHLIYAFLGIEE 70
            ::..|..||...|.::..:::.|::||..:.|..|.||.|....::|..|  ||||:|.:.|: :
  Fly     1 MRFQLFYILGLLSVTSLTHAASNLICYYDSNSYLRQGLAKMHTNELDLALQFCTHLVYGYAGL-K 64

  Fly    71 TGQLRVIDAYLDLEENSGRGNIKSFNALKLKNPVLKTLVAVGGWNE-----GSKRFSLVARDPSK 130
            :|.|.:....:||:    ....|...||:.|.|.||.|::|||..:     .:|...|:..:.:.
  Fly    65 SGTLELFSLNVDLD----MFYYKDITALRQKFPQLKILLSVGGDRDVDEAHPNKYVELLEANRTA 125

  Fly   131 REKFVDDVVRFLQRHGFDGLDLDWEYPGQR----H-SLDN--------------------EDRSN 170
            ::.|:|..:..|:|:|||||||.::.|..:    | ||.:                    |.:|.
  Fly   126 QQNFIDSSMILLKRNGFDGLDLAFQLPRNKPRKVHGSLGSYWKSFKKLFTGDFVVDPQAEEHKSQ 190

  Fly   171 YITFLKELKEGLEPFGFILSAAVGSAQFSAEISYDIPAMVPYLDLINVMAYD----LHGPWDQVV 231
            :...:..:|........:||..| ....::...:|:|.:.|..|.||:.|:|    |..|  :..
  Fly   191 FTDLVGNIKNAFRSANLMLSLTV-LPNVNSTWYFDVPKLHPQFDYINLAAFDFLTPLRNP--EEA 252

  Fly   232 GINAPLYAAEKDASDSSGRQQQLNVDAVVKYWLKAGAPAEKLILGVPFYGRSFTLATAEGNQPGA 296
            ...||::     ..|...|...|||:..:.|||:...|.:||.||:..|||::.|:...| ..||
  Fly   253 DFTAPIF-----FQDEQNRLPHLNVEFQINYWLQNHCPGQKLNLGIASYGRAWKLSKGSG-LSGA 311

  Fly   297 P--HIGKGIAGN----YSREPGVLGYNELCEMMERE----------------EWTQKWEATQQVP 339
            |  |...|:|..    .|.| |:|.:.|:|..:.:.                :.|||:.     .
  Fly   312 PIVHETCGVAPGGIQIQSAE-GLLSWPEICSKLSQNASAQYRGELAPLRKVTDLTQKYG-----N 370

  Fly   340 YAYRQRQ-------WVGYEDPRSLALKAQYVMDNHLGGIMIWSLESDDFRGTCGQQPYPLLHEI 396
            ||.|...       |:.::||....:||.|.....||||.::.|..|||||.|..|.||:|..|
  Fly   371 YALRPADDNGDFGVWLSFDDPDFAGIKAVYAKGKGLGGIALFDLSYDDFRGLCTGQKYPILRSI 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht8	NP_611542.2	GH18_chitolectin_chitotriosidase	31..400	CDD:119351	123/431 (29%)
		Glyco_18	31..379	CDD:214753	112/412 (27%)
		CBM_14	424..476	CDD:279884
Idgf1	NP_477258.1	GH18_IDGF	23..438	CDD:119352	124/432 (29%)
Idgf1	NP_477258.1	Glyco_18	24..417	CDD:214753	112/412 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463813
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840