DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht8 and RGD1309110

DIOPT Version :9

Sequence 1:	NP_611542.2	Gene:	Cht8 / 37390	FlyBaseID:	FBgn0034580	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	XP_006233175.1	Gene:	RGD1309110 / 295352	RGDID:	1309110	Length:	440	Species:	Rattus norvegicus

Alignment Length:	405	Identity:	140/405 - (34%)
Similarity:	217/405 - (53%)	Gaps:	26/405 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VSGLVKLLLGVILMAASSSAQGNSSKNVVCYQGTWSVYRPGLGKFGMEDIDPFLCTHLIYAFLGI 68
            :|.|| .::|:.|:.   :.|.:|:..::||...|..|:|.:....::||||.|||||||:|.||
  Rat    18 ISKLV-FIMGLNLLL---NVQLDSAYQLMCYFNNWPQYQPDVRGMKLDDIDPCLCTHLIYSFAGI 78

  Fly    69 EETGQLRVIDAYLDLEENSGRGNIKSFNALKLKNPVLKTLVAVGGWNEGSKRFSLVARDPSKREK 133
            .|..........||        :.|.||.||.:|..||||:::|.||..:..|..:...|..|..
  Rat    79 WENNNTMTKRKDLD--------DYKEFNDLKKRNNKLKTLLSIGCWNFEAGLFITMVSTPESRHT 135

  Fly   134 FVDDVVRFLQRHGFDGLDLDWEYPGQRHSLDNEDRSNYITFLKELKEGLE-------PFGFILSA 191
            |:..|.:||:::|||||:|.|:||| .:....:|:..:....:|:::..|       ....|::|
  Rat   136 FITSVRKFLRKYGFDGLNLAWQYPG-CYGSPPKDKHLFTILTQEIRKAFEKEVSKNKKSRLIITA 199

  Fly   192 AVGSAQFSAEISYDIPAMVPYLDLINVMAYDLHGPWDQVVGINAPLYAAEKDASDSSGRQQQLNV 256
            |:.......:..|.:|.:...||.|.||.|||||.||...|.|:|||.:..:    :|.:...|:
  Rat   200 ALAGVISPIQFGYHVPQLSQSLDYIQVMTYDLHGSWDGYTGENSPLYKSPAE----TGVKAFYNI 260

  Fly   257 DAVVKYWLKAGAPAEKLILGVPFYGRSFTLATAEGNQPGAPHIGKGIAGNYSREPGVLGYNELCE 321
            ...:..|...|...||||:|.|.||.:|.|:.:...:.|||....|..|.|:::.|...|.|:|.
  Rat   261 KYTMHNWKNKGVSPEKLIVGFPAYGHTFILSDSTKTEIGAPSNRGGHPGPYTKKTGFWAYYEICA 325

  Fly   322 MMEREEWTQKWEATQQVPYAYRQRQWVGYEDPRSLALKAQYVMDNHLGGIMIWSLESDDFRGT-C 385
            .::... .|.|.|.||||||:...:||||::.:|..:|||::.:|:.||.|||::..||:.|: |
  Rat   326 FLKNGA-IQVWNAAQQVPYAFHGNEWVGYDNVKSFHIKAQWLKNNNFGGAMIWAIGMDDYTGSFC 389

  Fly   386 GQQPYPLLHEINRVL 400
            .|.|:||...:...|
  Rat   390 DQGPFPLTSTLKNAL 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht8	NP_611542.2	GH18_chitolectin_chitotriosidase	31..400	CDD:119351	132/376 (35%)
		Glyco_18	31..379	CDD:214753	124/354 (35%)
		CBM_14	424..476	CDD:279884
RGD1309110	XP_006233175.1	GH18_chitolectin_chitotriosidase	41..404	CDD:119351	132/376 (35%)
RGD1309110	XP_006233175.1	Glyco_18	43..382	CDD:214753	124/352 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	338	1.000	Inparanoid score	I2302
OMA	1	1.010	-	-		QHG58170
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100224
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.880