DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cht8 and Chi3l3

DIOPT Version :9

Sequence 1:	NP_611542.2	Gene:	Cht8 / 37390	FlyBaseID:	FBgn0034580	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	XP_008759605.2	Gene:	Chi3l3 / 295351	RGDID:	1308790	Length:	401	Species:	Rattus norvegicus

Alignment Length:	407	Identity:	148/407 - (36%)
Similarity:	218/407 - (53%)	Gaps:	33/407 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LVKLLLGVILMAASSSAQGNSSKNVVCYQGTWSVYRPGLGKFGMEDIDPFLCTHLIYAFLG---- 67
            :.||:|...| |....|...||..::||..:|:..||.:|.|.:.:|||.|||||||||.|
  Rat     1 MAKLILATGL-AILLYAHLGSSYQLMCYYTSWAKDRPTVGSFKIGNIDPCLCTHLIYAFAGMRNN 64

  Fly    68 -IEETGQLRVIDAYLDLEENSGRGNIKSFNALKLKNPVLKTLVAVGGWNEGSKRFSLVARDPSKR 131
             |..|.:..:||             .::.|.||.:|..||||:|:|||..||..||.:...|..|
  Rat    65 EIINTSEQDLID-------------YEAINYLKDRNTELKTLLAIGGWKFGSAPFSAMVSTPQNR 116

  Fly   132 EKFVDDVVRFLQRHGFDGLDLDWEYPGQRHSLDNEDRSNYITFLKELKEGLEPFG-------FIL 189
            :.|:..|::||:::.||||:|||:|||.|.| ..:|:..:...::|:::..|...       .:|
  Rat   117 QTFIKSVIKFLRQYKFDGLNLDWQYPGSRGS-PPKDKHLFSVLVQEMRKAFEKESTEQEIPRLLL 180

  Fly   190 SAAVGSAQFSAEISYDIPAMVPYLDLINVMAYDLHGPWDQVVGINAPLYAAEKDASDSSGRQQQL 254
            :|.|.....:.:..|.||.:...||...||.|:||...:.....|:|||.:..|    :|....|
  Rat   181 TATVAGVIDTIQSGYKIPELSQSLDYFQVMTYNLHDFQNGYTRENSPLYQSPSD----TGIYAYL 241

  Fly   255 NVDAVVKYWLKAGAPAEKLILGVPFYGRSFTLATAEGNQPGAPHIGKGIAGNYSREPGVLGYNEL 319
            ||||::.||...||..||||:|.|.||.:|.|:........||.:..|..|.::.|.|:..|.|:
  Rat   242 NVDAIISYWKDNGAAREKLIVGFPAYGHNFILSDPSNTGINAPIVSTGPPGKFTGEAGLWAYYEI 306

  Fly   320 CEMMEREEWTQKWEATQQVPYAYRQRQWVGYEDPRSLALKAQYVMDNHLGGIMIWSLESDDFRGT 384
            |..: .:..|..|:..|:||||.:...||||::.:|..:|||::.||.|||.|:|.|:.|||.|:
  Rat   307 CTFL-NDGATDLWDGPQEVPYAVQGNVWVGYDNVKSFKIKAQWLKDNKLGGAMVWPLDMDDFTGS 370

  Fly   385 -CGQQPYPLLHEINRVL 400
             |.|..:||...:...|
  Rat   371 FCQQGRFPLTSTLKHYL 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht8	NP_611542.2	GH18_chitolectin_chitotriosidase	31..400	CDD:119351	139/381 (36%)
		Glyco_18	31..379	CDD:214753	131/359 (36%)
		CBM_14	424..476	CDD:279884
Chi3l3	XP_008759605.2	GH18_chitolectin_chitotriosidase	24..387	CDD:119351	139/381 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	338	1.000	Inparanoid score	I2302
OMA	1	1.010	-	-		QHG58170
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.080