DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht8 and cht-4

DIOPT Version :9

Sequence 1:	NP_611542.2	Gene:	Cht8 / 37390	FlyBaseID:	FBgn0034580	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_497437.2	Gene:	cht-4 / 189507	WormBaseID:	WBGene00021252	Length:	360	Species:	Caenorhabditis elegans

Alignment Length:	379	Identity:	109/379 - (28%)
Similarity:	175/379 - (46%)	Gaps:	51/379 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 VVCYQGTWSVYRPGLGKFGMEDIDPFLCTHLIYA-FLGIEETGQLRVIDAYLDLEENSG--RGNI 92
            |.||   :.:.:|.:.|     :...||||:|.. ...:.|.|:|:..:.  |||..|.  .|.|
Worm    20 VACY---YILNQPDISK-----VPKNLCTHIILINSAHVSEDGRLQGFEQ--DLEHFSELFDGKI 74

  Fly    93 KSFNALKLKNPVLKTLVAVGGWNEGSKRFSLVARDPSKREKFVDDVVRFLQRHGFDGLDLDWEYP 157
            :.|.::...||                .||.:..:.:....|...|.:.||::..:|:|:|||:|
Worm    75 ELFVSITSSNP----------------SFSFLTSNTTLMHNFSSTVTQVLQKYRLNGVDIDWEFP 123

  Fly   158 GQRHSLDNEDRSNYITFLKELKEGLEPFGFILSAAVGSAQFSAEISYDIPAMVPYLDLINVMAYD 222
            .........|::::.|||:.||..|:|....||.||......:..:||:.|:..|.|::.:|.||
Worm   124 VWSRDAQKSDKAHFATFLRILKSHLKPADLKLSVAVSGPPTISRKAYDVDALKMYADMVQIMNYD 188

  Fly   223 LH------GPWDQVVGINAPLYAAEKDASDSSGRQQQLNVDAVVKYWLKAGAPAEKLILGVPFYG 281
            .|      .|:   ||.||||:....:.|...    ::|.:|.:|.|...|.|......|:|.|.
Worm   189 FHVFNRYSNPF---VGFNAPLHPMRAEISVLG----EMNAEASMKTWYDLGLPRNISFFGIPTYA 246

  Fly   282 RSFTLATAEGNQPGAPHIGKGIAGNYSREPGVLGYNELCEMMEREEWTQKWEATQQVPYAYRQRQ 346
            |:|.|.|...::|.:|.|        ...|.:....::|...:...:|..|....|.||.|....
Worm   247 RAFQLLTHYLHKPYSPAI--------RARPEITNLPDVCIFAQSGYYTTVWNHHAQAPYLYGDDG 303

  Fly   347 -WVGYEDPRSLALKAQYVMDNHLGGIMIWSLESDDFRGTCGQQPYPLLHEINRV 399
             ||.||:.:|:..|..:.....:||:|::|:.|||..|.||..|||||.:|:::
Worm   304 IWVSYENQQSILAKMAFARKLQVGGVMVFSIGSDDVTGKCGHGPYPLLTKISKL 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht8	NP_611542.2	GH18_chitolectin_chitotriosidase	31..400	CDD:119351	109/379 (29%)
		Glyco_18	31..379	CDD:214753	97/357 (27%)
		CBM_14	424..476	CDD:279884
cht-4	NP_497437.2	GH18_chitinase-like	30..357	CDD:385673	105/364 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920