DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cht8 and chil-17

DIOPT Version :9

Sequence 1:	NP_611542.2	Gene:	Cht8 / 37390	FlyBaseID:	FBgn0034580	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_496019.1	Gene:	chil-17 / 187733	WormBaseID:	WBGene00011159	Length:	435	Species:	Caenorhabditis elegans

Alignment Length:	420	Identity:	102/420 - (24%)
Similarity:	180/420 - (42%)	Gaps:	90/420 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VSGLVKLLLGVILMAASSSA-----QGNSSKNVV-----CYQ---GTWSVY------RPGLGKFG 49
            :||:. |..|::..|.::..     :...|||.|     |.:   |.:|.|      :..|.|.
Worm    36 ISGIF-LFCGIVSYALTTFVFHFYKEDKFSKNEVGLDPICKRRIVGYYSEYDSTDISKNQLAKL- 98

  Fly    50 MEDIDPFLCTHLIYAFLGIEETGQLRVIDAYLDLEENSGRGNIKSFNALKLK----NPVLKTLVA 110
                     ||.::||:.|:..|.|:..:...:          :.|.:||.|    :..||.:.:
Worm    99 ---------THAVFAFVDIKYDGTLQFKNLITE----------QKFFSLKSKARSLHSNLKLMFS 144

  Fly   111 VGGWNEGSKRFSLVARDPSKREKFVDDVVRFLQRHGFDGLDLDWEYPGQRHSLDNEDRSNYITFL 175
            :|| :|.|..||....:...:...:..::.|:..|..||:||.|::|..|      |:|||.|.:
Worm   145 IGG-DENSFDFSSALANTQMKSTLITSIIAFIHSHMIDGVDLHWKWPTSR------DKSNYATLI 202

  Fly   176 KELKEGLEPFG--FILSAAVGSAQFSA-EISYDIPAMVPYLDLINVMAYDLHGP----WDQVVGI 233
            :|::|.::...  .|:|..:.....|. |..:|:.|:..::|.|||.:.|...|    |....|.
Worm   203 REIREKVDELDAKIIISITIPPVGVSDWESGFDLDAIQKHVDFINVHSMDYAKPLPNQWGTPTGP 267

  Fly   234 NAPLYAAEKDASDSSGRQQQLNVDAVVKYWLKAGAPAEKLILGVPFYGRSFTLATAEGNQPGAPH 298
            :|.:       :.:.|.:|..|||..:|::.........:.|.:|||.|.:            .:
Worm   268 SASM-------NFNIGLRQHYNVDWTMKHYTCELKKPSMINLVIPFYVRMW------------KN 313

  Fly   299 IGKGIAGNYS-------REPGVLGYNELCE-MMEREEW---TQKWEATQQVPYA--YRQRQWVGY 350
            :.|.|.....       ::..|.|.::|.. .:|.|:.   .:.|:...|.||.  .:.|.:..|
Worm   314 VQKAIDNRTEVFRNVELKDNEVEGRSQLSRYTVEHEDMELSPESWDNATQTPYVLDLKTRTFFTY 378

  Fly   351 EDPRSLALKAQYVMDNHLGGIMIWSLESDD 380
            |:.:|:.:|..||....|||:.|||::.||
Worm   379 ENEKSIKVKLDYVNKMDLGGVWIWSVDMDD 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht8	NP_611542.2	GH18_chitolectin_chitotriosidase	31..400	CDD:119351	94/388 (24%)
		Glyco_18	31..379	CDD:214753	92/385 (24%)
		CBM_14	424..476	CDD:279884
chil-17	NP_496019.1	Glyco_18	77..407	CDD:214753	90/375 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164335
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1289629at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4747
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.750