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Protein Alignment Cht8 and CHIT1

DIOPT Version :9

Sequence 1:	NP_611542.2	Gene:	Cht8 / 37390	FlyBaseID:	FBgn0034580	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_003456.1	Gene:	CHIT1 / 1118	HGNCID:	1936	Length:	466	Species:	Homo sapiens

Alignment Length:	486	Identity:	186/486 - (38%)
Similarity:	263/486 - (54%)	Gaps:	59/486 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 VILMAASSSAQGNSSKNVVCYQGTWSVYRPGLGKFGMEDIDPFLCTHLIYAFLGIEETGQLRVID 78
            |:||....||     ..:|||...|:.||.|..:|..:|:||.|||||||||.|        :.:
Human    12 VLLMIPWGSA-----AKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAG--------MTN 63

  Fly    79 AYLDLEENSGRGNIKSFNALKLKNPVLKTLVAVGGWNEGSKRFSLVARDPSKREKFVDDVVRFLQ 143
            ..|...|.:.....:.||.||..||.||||:|:||||.|:::|:.:....:.|:.||:..:|||:
Human    64 HQLSTTEWNDETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLR 128

  Fly   144 RHGFDGLDLDWEYPGQRHSLDNEDRSNYITFLKEL------------KEGLEPFGFILSAAVGSA 196
            ::.||||||||||||.:.| ...|:..:.|.:::|            ||.|     :|||||.:.
Human   129 KYSFDGLDLDWEYPGSQGS-PAVDKERFTTLVQDLANAFQQEAQTSGKERL-----LLSAAVPAG 187

  Fly   197 QFSAEISYDIPAMVPYLDLINVMAYDLHGPWDQVVGINAPLYAAEKDASDSSGRQQQLNVDAVVK 261
            |...:..|::..:...||.:|:||||.||.|::|.|.|:|||..:::    ||....|||||.|:
Human   188 QTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEE----SGAAASLNVDAAVQ 248

  Fly   262 YWLKAGAPAEKLILGVPFYGRSFTLATAEGNQPGAPHIGKGIAGNYSREPGVLGYNELCEMMERE 326
            .||:.|.||.|||||:|.||||||||::...:.|||..|.|..|.:::|.|:|.|.|:|
Human   249 QWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVC------ 307

  Fly   327 EW---TQKWEATQQVPYAYRQRQWVGYEDPRSLALKAQYVMDNHLGGIMIWSLESDDFRG-TCGQ 387
            .|   |::....|:|||.:|..||||::|..|...|..|:....|||.|:|:|:.|||.| :|.|
Human   308 SWKGATKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQ 372

  Fly   388 QPYPLLHEINRVLFGGNTPSGLTTE------------SNRESPSEGFSCPADAPAGYIRDPDNCS 440
            ..|||:..:.:.|.....||| |.|            .:..||.:...|...|. |...:|...|
Human   373 GRYPLIQTLRQELSLPYLPSG-TPELEVPKPGQPSEPEHGPSPGQDTFCQGKAD-GLYPNPRERS 435

  Fly   441 KFYYCSGGKTHNFDCPSGLNFDLDTKSCNYS 471
            .||.|:.|:.....||:||.|....|.|.::
Human   436 SFYSCAAGRLFQQSCPTGLVFSNSCKCCTWN 466

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.