Protein Alignment cpa and CAPZA3

DIOPT Version :9

• Sequence 1: NP_611539.1
• Gene: cpa / 37387
• FlyBaseID: FBgn0034577
• Length: 286
• Species: Drosophila melanogaster
• Sequence 2: NP_201585.1
• Gene: CAPZA3 / 93661
• HGNCID: 24205
• Length: 299
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 92/280 - (32%)
• Similarity: 156/280 - (55%)
• Gaps: 10/280 - (3%)

  Fly     1 MEQTPITDAEKVRIVSDFILHAPPGEFNEVFNDVRELLKNDTLLKDGASHAFAQYNKDQLTPVRI 65
            |..:.::..:|.|::...:|.||||||...|:|:..|::::.|:......|..|:.:....|:.|
Human     1 MTLSVLSRKDKERVIRRLLLQAPPGEFVNAFDDLCLLIRDEKLMHHQGECAGHQHCQKYSVPLCI 65

  Fly    66 EGTDHNAIISEHNDLGNGRFYDPRTKQAFKYDHLRKEASDYQD---VEADATAEPWRAALDLETL 127
            :|  :..::|.||.:|:.||:|.::|.:||||.|:.:..|.|.   ::.:  ||..|..|.....
Human    66 DG--NPVLLSHHNVMGDYRFFDHQSKLSFKYDLLQNQLKDIQSHGIIQNE--AEYLRVVLLCALK 126

  Fly   128 AYTASHYRHGVSSVFGKAQGNQITLTICIEDHQFQPKNYWNGRWRSQWHVTFQAGSGTAELKGVL 192
            .|...||..|..::..|...::..|..|||||.::....|||.|:|:|  .||......::.|.:
Human   127 LYVNDHYPKGNCNMLRKTVKSKEYLIACIEDHNYETGECWNGLWKSKW--IFQVNPFLTQVTGRI 189

  Fly   193 KVQVHYYEDGNVQLVSSKECRESVVVSNEQQVAKEVIRLIEDAENEYQLAISENYQTMSDTTF-K 256
            .||.|::...|:.:..||:.:||:.:.|:.|:|....||:|:.||::|.|:.|..|.:|:... |
Human   190 FVQAHFFRCVNLHIEISKDLKESLEIVNQAQLALSFARLVEEQENKFQAAVLEELQELSNEALRK 254

  Fly   257 AMRRQLPITRTKIDWSKIVS 276
            .:||.||:|||.|||.:|:|
Human   255 ILRRDLPVTRTLIDWHRILS 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cpa	NP_611539.1	F-actin_cap_A	15..284	CDD:396017	89/266 (33%)
CAPZA3	NP_201585.1	F-actin_cap_A	12..274	CDD:279591	89/267 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0836
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1085166at2759
OrthoFinder	1	1.000	-	-		FOG0001352
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10653
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X840
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.880