DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cpa and Capza3

DIOPT Version :9

Sequence 1:	NP_611539.1	Gene:	cpa / 37387	FlyBaseID:	FBgn0034577	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	NP_058860.2	Gene:	Capza3 / 29324	RGDID:	2271	Length:	299	Species:	Rattus norvegicus

Alignment Length:	279	Identity:	91/279 - (32%)
Similarity:	156/279 - (55%)	Gaps:	8/279 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEQTPITDAEKVRIVSDFILHAPPGEFNEVFNDVRELLKNDTLLKDGASHAFAQYNKDQLTPVRI 65
            |..:.::..:|.:::...::.||||||...|:|:..|::::.|:......|..|:.:....|:.|
  Rat     1 MSLSVLSRQDKEKVIHRLLIQAPPGEFVNAFDDLCLLIRDEKLMHHQGECAGHQHCQKYCVPLCI 65

  Fly    66 EGTDHNAIISEHNDLGNGRFYDPRTKQAFKYDHLRKEASDYQD--VEADATAEPWRAALDLETLA 128
            :|  :..::|.||.:|:.||:|.::|.:|::|.|:.:..|.|.  :..:.| |..|:.:......
  Rat    66 DG--NPVLLSHHNVMGDFRFFDYQSKLSFRFDLLQNQLRDIQSHGIIRNET-EYLRSVVMCALKL 127

  Fly   129 YTASHYRHGVSSVFGKAQGNQITLTICIEDHQFQPKNYWNGRWRSQWHVTFQAGSGTAELKGVLK 193
            |...||.:|..:|..|...|:..|..|||||.:.....|||.|:|:|  .||......::.|.:.
  Rat   128 YVNDHYPNGNCNVLRKTVKNKEFLIACIEDHSYDNGECWNGLWKSKW--IFQVNPFLTQVTGRIF 190

  Fly   194 VQVHYYEDGNVQLVSSKECRESVVVSNEQQVAKEVIRLIEDAENEYQLAISENYQTMSDTTF-KA 257
            ||.||:...|:.:..||:.:||:.|.|:.|:|....||:|:.||::|.|:.|..|.:|:... |.
  Rat   191 VQAHYFRCVNLHVEVSKDLKESLEVVNQAQLALSFARLVEEQENKFQAAVIEELQELSNEALRKI 255

  Fly   258 MRRQLPITRTKIDWSKIVS 276
            :||.||:|||.|||.:|:|
  Rat   256 LRRDLPVTRTLIDWQRILS 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cpa	NP_611539.1	F-actin_cap_A	15..284	CDD:396017	89/265 (34%)
Capza3	NP_058860.2	F-actin_cap_A	15..274	CDD:396017	88/263 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0836
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1085166at2759
OrthoFinder	1	1.000	-	-		FOG0001352
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10653
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X840
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.880