DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cpa and cap-1

DIOPT Version :9

Sequence 1:	NP_611539.1	Gene:	cpa / 37387	FlyBaseID:	FBgn0034577	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	NP_501145.1	Gene:	cap-1 / 177497	WormBaseID:	WBGene00000292	Length:	282	Species:	Caenorhabditis elegans

Alignment Length:	283	Identity:	158/283 - (55%)
Similarity:	197/283 - (69%)	Gaps:	8/283 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ITDAEKVRIVSDFILHAPPGEFNEVFNDVRELLKNDTLLKDGASHAFAQYNKDQLTPVRIEGTDH 70
            |:|||||||.||||.||||||||||||.||.||:||.|||:...:|.||||..|..||:::|...
Worm     4 ISDAEKVRIASDFIKHAPPGEFNEVFNSVRMLLENDDLLKNKCVNAIAQYNVGQFVPVKLDGVAK 68

  Fly    71 NAIISEHNDLGNGRFYDPRTKQAFKYDHLRKEASDYQDVEADA-TAEPWRAALDLETLAYTASHY 134
            ..:|:.:||||||||||..:|::|||||:||||:|.|...|:: ..|.||.||..:...|...||
Worm    69 QTLITPYNDLGNGRFYDEVSKKSFKYDHVRKEAADLQPHPAESGITEQWRQALQTQLDIYIDDHY 133

  Fly   135 -RHGVSSVFGKAQGNQITLTICIEDHQFQPKNYWNGRWRSQWHVTFQAG-SGTAELKGVLKVQVH 197
             :.|...||.:   |.: .|||||.|||||||:.||||||:|:|....| ||:.|:||.:..|||
Worm   134 AKSGTGVVFAR---NGV-FTICIESHQFQPKNFCNGRWRSEWNVPVGDGKSGSQEMKGKILSQVH 194

  Fly   198 YYEDGNVQLVSSKECRESVVVSNE-QQVAKEVIRLIEDAENEYQLAISENYQTMSDTTFKAMRRQ 261
            |||||||||.|.||....|.||.: .:.|||:|..|.:.|..||.|:.|||..||||||||:|||
Worm   195 YYEDGNVQLFSEKEPVLKVNVSADFDKTAKEIIHAISEEETIYQNAVQENYANMSDTTFKALRRQ 259

  Fly   262 LPITRTKIDWSKIVSYSIGKELK 284
            ||:||.|:||:|..:|.||:|:|
Worm   260 LPVTRAKMDWNKAQTYRIGQEMK 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cpa	NP_611539.1	F-actin_cap_A	15..284	CDD:396017	149/272 (55%)
cap-1	NP_501145.1	F-actin_cap_A	10..280	CDD:279591	151/273 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158912
Domainoid	1	1.000	284	1.000	Domainoid score	I863
eggNOG	1	0.900	-	-		E1_KOG0836
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H24376
Inparanoid	1	1.050	299	1.000	Inparanoid score	I1642
Isobase	1	0.950	-	0	Normalized mean entropy	S1021
OMA	1	1.010	-	-		QHG54328
OrthoDB	1	1.010	-	-		D1085166at2759
OrthoFinder	1	1.000	-	-		FOG0001352
OrthoInspector	1	1.000	-	-		oto18689
orthoMCL	1	0.900	-	-		OOG6_102492
Panther	1	1.100	-	-	LDO	PTHR10653
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R166
SonicParanoid	1	1.000	-	-		X840
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	16.790