Protein Alignment shg and cdh-9

DIOPT Version :10

• Sequence 1: NP_476722.1
• Gene: shg / 37386
• FlyBaseID: FBgn0003391
• Length: 1507
• Species: Drosophila melanogaster
• Sequence 2: NP_510685.2
• Gene: cdh-9 / 186608
• WormBaseID: WBGene00000401
• Length: 623
• Species: Caenorhabditis elegans
• Alignment Length: 853
• Identity: 177/853 - (20%)
• Similarity: 283/853 - (33%)
• Gaps: 323/853 - (37%)

  Fly    44 LGRRLIPARLLLGVIVAISLLSPALALHSPPDKNFSG-DNRKPAFKNCAGYAPKVKEEQPENTYV 107
            |||.|    |||.::...|  :..|..:.......|. ::.||.  |..|..|...:...|....
 Worm     5 LGRSL----LLLALLAQYS--NTCLLKNGMSSVYLSAFEDLKPG--NVIGTLPFESQTSKETDVE 61

  Fly   108 LTV----EAVDPDPDQVIRYSIVQSPFERPKFFINPSTGVIFTTHTFDRDEPIHEKFVFVTVQAT 168
            |.|    |.||                      :.|.:..:....|.||||.: .||..|....:
 Worm    62 LRVVKGNELVD----------------------VKPGSHDLILKKTLDRDEGV-GKFEAVVECRS 103

  Fly   169 DNGLPPLD-DVCTFN----VTIEDINDNAPAFNKARYDESMSENAQPDAVVMT-ISASDFDD-GN 226
            .|    || |....|    ||::|||||||.|:.|.|...:.|......:|.| ..|:|.|. |.
 Worm   104 SN----LDTDFSQLNISVFVTVKDINDNAPVFDSAEYFVDIKEELPTGTIVFTDFEATDNDQPGP 164

  Fly   227 NSLVEYEILRERDFQYFKIDKESGIIYLKRPIDKRPGQSYAIIVRAYNVVPDPPQDAQIEVRIRV 291
            ||.|:|.|:......:.:|                               |||
 Worm   165 NSFVQYTIVAGPHSHFLEI-------------------------------PDP------------ 186

  Fly   292 VESSIKPPSFVNPIDTPIYLKENLKNFTHPIATLRAVSNMPDKPEVIFELNTGRTEQTNSKNTFV 356
                .||
 Worm   187 ----FKP---------------------------------------------------------- 189

  Fly   357 FNQIGNEVTISLGKTLDYEAITDYTLTMIVRNTHE--LGTEHQIKIQVEDVNDNIP-----YYT- 413
                    .|::...::||.|..:::.:..|:..|  |.:...:.:.:.||||.:|     :||
 Worm   190 --------VITIKDRINYEEIKKFSVEIEARDQGEPSLASTVPLHVTIVDVNDLLPRFKHSHYTA 246

  Fly   414 -EVKSGTILENEPPGTPVMQVRAFDMDGTSANNIVSF--ELADNREYFTIDPNTGNITALT---- 471
             ..|:| :|..||..     :.|.|.|..:|:.|.|.  ||:   |:|.|| |.|:|.::|
 Worm   247 KSQKNG-VLVFEPEA-----ISAQDGDRLNASLIFSLSGELS---EHFAID-NDGSIRSITPNPP 301

  Fly   472 ---TF-----DREERDFYNVKVIASDNSPSSLFDNGEPNRGHQVFRISIGDKNDHKPHFQQDKYL 528
               ||     :||:.: .|...|.|....|||                         .||.:.|
 Worm   302 QRATFFVTASEREDTE-RNSTAILSIRLQSSL-------------------------AFQHNTY- 339

  Fly   529 AERLLEDANTNTEVIEVKAEDEDNASQILYSIESGNVGDAFKIGLK--TGKITVNQKLDY-ETIT 590
            :..:.......:.||.|.|..|:| :.:.||:    :.|...:.:.  :|.:.:.:||:. ||
 Worm   340 STTISPTTPIGSTVITVVANSENN-TPLTYSL----LADTNTVSIDEVSGNVVLRKKLEKPET-- 397

  Fly   591 EYELKVRAFDGIYDDYTTVVIKIEDVND-----NPPVF-KQDYSVTILEETTYDDCILTVEAYDP 649
               |.|.|.||  ::..:..:.:...|.     :|..| |.:|.:||.:..     :|.|.
 Worm   398 ---LNVTASDG--ENVVSTALHLMTANSEESCRSPIKFEKFEYKMTIGKLN-----VLGVV---- 448

  Fly   650 DIKDRNADQH----IVYSIHQNDGNRWTIDNSGCLRLVKTLDRDPPNGH---KNWQVLIKANDED 707
                 ||...    |.| |..|..|.:.||.:|.::|:       |...   |..::::.|..
 Worm   449 -----NATSRTGTKITY-ILMNMNNDFEIDTNGVVKLL-------PKARLQCKVCELIVVAKS-- 498

  Fly   708 GVGTTVSTVKEVTVTLKDIN-DNAPFLINEMPVY--------------------------WQENR 745
              ||.::..|        || ||..|:::.....                          |:...
 Worm   499 --GTQMAITK--------INVDNPAFVLHSTTALTLLILIILCLIFTMLAILVCRKFCEKWKTGH 553

  Fly   746 NPGHVVQLQANDYDDTPGAGNFTFGID-SEATPDIKTKFSMDGD---YLHANVQFDREAQKEYFI 806
            ....:..|  |...||        ||. :..||:..|::.::.|   ...:.....:.:|..:.:
 Worm   554 RRSSICWL--NGTTDT--------GISITTTTPNTTTRYVVNSDRDRCYESKSPGPKRSQGAHLV 608

  Fly   807 PIRISDSG 814
            |:.::..|
 Worm   609 PVTVTSDG 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shg	NP_476722.1	Cadherin_repeat	93..191	CDD:206637	26/106 (25%)
		Cadherin_repeat	200..292	CDD:206637	17/93 (18%)
		CA	332..410	CDD:214520	11/79 (14%)
		Cadherin_repeat	417..518	CDD:206637	30/114 (26%)
		Cadherin_repeat	531..619	CDD:206637	20/95 (21%)
		Cadherin_repeat	627..729	CDD:206637	24/109 (22%)
		Cadherin_repeat	736..834	CDD:206637	14/109 (13%)
		LamG	1127..1294	CDD:238058
		CADH_Y-type_LIR	1430..1489	CDD:460041
cdh-9	NP_510685.2	CA_like	<80..129	CDD:481204	20/53 (38%)
		Cadherin_repeat	135..234	CDD:206637	28/211 (13%)